The VectorBase Aedes data release consists of 17,776 gene predictions. These genes were predicted using the Ensembl annotation pipeline and represent models generated by GeneWise (E. Birney) from protein similarities and by Exonerate (G. Slater) from Aedes transcript similarities (EST and cDNA). Some filtering to remove potential transposon sequences has been implemented. Currently, 12,250 of the predictions map to EST alignments.
The TIGR Aedes data release includes a set of 28,301 consensus gene predictions. These genes were modeled based on a combination of Augustus (M. Stanke), GlimmerHMM (M. Pertea), Genie (D. Kulp), and Twinscan (M. Brent) gene predictions, coupled with protein and EST genome alignments. The consensus gene models included in this release encode proteins with matches to other known proteins, signal peptides, transmembrane domains, or matches to Pfam or TIGRfam domains. 12,277 genes mapped to EST alignments, providing evidence of expression. 18,006 have a Blast match to an Anopheles gambiae protein and 13,744 have a Blast match to a Drosophila melanogaster protein (E=1e-10). Please note that the genes in this TIGR release do not have permanent accessions. This gene set is considered preliminary, and the genes may or may not be in the final release. [Aedes agypti homepage].
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