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Karyotype

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About the Bos taurus genome

Assembly

Btau_4.0, released on 4 october 2007, is a preliminary assembly of the bovine, Bos taurus, Hereford breed. The Btau_4.0 assembly used a combined strategy as developed for the rat genome (Nature 428:493-521, 2004) and used more recently for the sea urchin genome (Science 314:941-952, 2006). The combined strategy is a hybrid of the Whole Genome Shotgun (WGS) approach used for the mouse genome and the hierarchical (BAC clone) approach used for the human genome. The sequencing combines BAC shotgun reads with whole-genome-shotgun (WGS) reads from small insert libraries as well as BAC end sequences.

This assembly adds relatively little new sequence data, and thus contigs and scaffolds are not significantly changed, but use different map information than was used for the Btau_3.1 assembly to place the contigs and scaffolds in the genome, resulting in more accurate chromosome structures.

The N50 size is the length such that 50% of the assembled genome lies in blocks of the N50 size or longer. The N50 size of the contigs is 48.7 kb and the N50 of the scaffolds is 1,922 kb. The total length of all contigs is 2.73 Gb. When the gaps between contigs in scaffolds are included, the total span of the assembly is 2.87 Gb. The coverage is 7x.

The project coordination and genome sequencing and assembly is provided by the Human Genome Sequencing Center at Baylor College of Medicine.

Annotation

This is a full genebuild on the assembly 4.0 in the standard Ensembl way.

What's New in Ensembl 50

Bos taurus News

• Cow Genebuild
  Ensembl 50 includes the latest Bos taurus assembly, Btau_4.0, and a corresponding new genebuild. As per the previous build, this is a normal Ensembl genebuild using the standard pipeline.
• New variation databases
  Ensembl 50 includes a new orangutan variation database, with SNPs called by Ensembl using ssaha2/pileup from reference assembly reads, plus remapping of SNPs to the new assemblies for tetraodon and cow.
  Read more...
• Syntenies
  New syntenies have been calculated for human vs orangutan and human vs cow.
• Non-coding genes
  These have been updated for most species, including an miRNA update and HGNC names where possible.
• Multiple alignments
  

  The multiple alignments are being extended with new species and 2X genomes.
  Read more...

More news...

Statistics

How the statistics are calculated