Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000694 Proline-rich region	545	4202	21	IPR003598 Immunoglobulin subtype 2	57	571
2	IPR000276 Rhodopsin-like GPCR superfamily	506	7305	22	IPR001440 Tetratricopeptide TPR_1	56	1014
3	IPR000719 Protein kinase	288	3264	23	IPR001128 Cytochrome P450	55	939
4	IPR001680 WD-40 repeat	155	1856	24	IPR007086 Zinc finger, C2H2-subtype	54	1307
5	IPR000504 RNA-binding region RNP-1 (RNA recognition motif)	140	914	25	IPR000315 Zinc finger, B-box	54	690
6	IPR003596 Immunoglobulin V-set, subgroup	132	1281	26	IPR000108 Neutrophil cytosol factor 2	48	930
7	IPR000210 BTB	101	1686	27	IPR000198 RhoGAP	46	314
8	IPR001806 Ras GTPase	96	977	28	IPR007087 Zinc finger, C2H2-type	46	459
9	IPR001841 Zinc finger, RING-type	94	459	29	IPR000742 EGF-like, type 3	44	971
10	IPR000008 C2 calcium-dependent membrane targeting	93	1014	30	IPR001664 Intermediate filament protein	44	295
11	IPR000533 Tropomyosin	92	564	31	IPR001478 PDZ/DHR/GLGF	44	377
12	IPR002110 Ankyrin	81	1271	32	IPR001993 Mitochondrial substrate carrier	43	512
13	IPR001611 Leucine-rich repeat	76	904	33	IPR001092 Basic helix-loop-helix dimerisation region bHLH	43	160
14	IPR000047 Helix-turn-helix motif, lambda-like repressor	66	749	34	IPR001304 C-type lectin	42	264
15	IPR002048 Calcium-binding EF-hand	65	416	35	IPR000357 HEAT	41	171
16	IPR000104 Antifreeze protein, type I	63	587	36	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	39	169
17	IPR000048 IQ calmodulin-binding region	61	1051	37	IPR001356 Homeobox	39	262
18	IPR000152 Aspartic acid and asparagine hydroxylation site	58	3866	38	IPR000219 DH	39	349
19	IPR001781 LIM, zinc-binding	57	1500	39	IPR001909 KRAB box	39	1175
20	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	57	406	40	IPR002198 Short-chain dehydrogenase/reductase SDR	38	379

View top 500 InterPro hits (large table)

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