Top 500 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000694 Proline-rich region	682	6486	251	IPR002952 Eggshell protein	9	39
2	IPR000276 GPCR, rhodopsin-like	360	5584	252	IPR001211 Phospholipase A2, eukaryotic	9	72
3	IPR000719 Protein kinase, core	298	3894	253	IPR002077 Voltage-dependent calcium channel, alpha-1 subunit	9	150
4	IPR001680 WD40 repeat	166	2374	254	IPR001753 Crotonase, core	9	30
5	IPR000504 RNA recognition motif, RNP-1	140	895	255	IPR001373 Cullin, N-terminal region	9	61
6	IPR001909 Krueppel-associated box	100	3729	256	IPR012336 Thioredoxin-like fold	9	14
7	IPR001781 Zinc finger, LIM-type	98	3377	257	IPR002659 Glycosyl transferase, family 31	9	9
8	IPR000210 BTB/POZ-like	98	1897	258	IPR002049 EGF-like, laminin	9	340
9	IPR001806 Ras GTPase	95	928	259	IPR000920 Myelin P0 protein	9	78
10	IPR000008 C2 calcium-dependent membrane targeting	93	1432	260	IPR005828 General substrate transporter	9	37
11	IPR001841 Zinc finger, RING-type	90	573	261	IPR003409 MORN motif	9	73
12	IPR003596 Immunoglobulin V-set, subgroup	86	1297	262	IPR001012 UBX	9	46
13	IPR002110 Ankyrin	84	1381	263	IPR008957 Fibronectin, type III-like fold	9	17
14	IPR000533 Tropomyosin	82	593	264	IPR001599 Alpha-2-macroglobulin	9	62
15	IPR001611 Leucine-rich repeat	77	806	265	IPR003594 ATP-binding region, ATPase-like	9	46
16	IPR000152 Aspartic acid and asparagine hydroxylation site	69	4645	266	IPR000804 Clathrin adaptor, sigma subunit/coatomer, zeta subunit	9	35
17	IPR002048 Calcium-binding EF-hand	65	433	267	IPR000569 HECT	9	98
18	IPR000048 IQ calmodulin-binding region	63	1143	268	IPR004843 Metallophosphoesterase	8	45
19	IPR000047 Helix-turn-helix motif, lambda-like repressor	63	757	269	IPR000759 Adrenodoxin reductase	8	114
20	IPR003598 Immunoglobulin subtype 2	62	703	270	IPR000407 Nucleoside phosphatase GDA1/CD39	8	14
21	IPR000104 Antifreeze protein, type I	61	598	271	IPR006670 Cyclin	8	29
22	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	60	546	272	IPR000591 Pleckstrin/ G-protein, interacting region	8	76
23	IPR001440 Tetratricopeptide TPR-1	55	876	273	IPR000994 Peptidase M24, catalytic core	8	33
24	IPR007086 Zinc finger, C2H2-subtype	54	1385	274	IPR002999 Tudor	8	47
25	IPR000198 RhoGAP	51	406	275	IPR000651 Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal	8	84
26	IPR001478 PDZ/DHR/GLGF	51	525	276	IPR001134 Netrin, C-terminal	8	83
27	IPR000219 Dbl homology (DH) domain	50	594	277	IPR006052 Tumor Necrosis Factor	8	38
28	IPR000315 Zinc finger, B-box	48	587	278	IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type	8	54
29	IPR001128 Cytochrome P450	47	939	279	IPR001107 Band 7 protein	8	48
30	IPR000372 Leucine-rich repeat, cysteine-rich flanking region, N-terminal	46	974	280	IPR002350 Proteinase inhibitor I1, Kazal	8	34
31	IPR000742 EGF-like, type 3	44	1078	281	IPR005024 Snf7	8	8
32	IPR002198 Short-chain dehydrogenase/reductase SDR	44	494	282	IPR000734 Lipase	8	106
33	IPR001356 Homeobox	44	354	283	IPR000853 Nematoda metallothionein, family 6	8	58
34	IPR002126 Cadherin	44	1338	284	IPR000327 POU-specific	8	103
35	IPR001452 Src homology-3	44	427	285	IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal	8	36
36	IPR001993 Mitochondrial substrate carrier	44	558	286	IPR006680 Amidohydrolase 1	8	20
37	IPR000884 Thrombospondin, type I	42	931	287	IPR000079 High mobility group protein HMG14 and HMG17	8	66
38	IPR000108 Neutrophil cytosol factor 2	42	978	288	IPR001388 Synaptobrevin	8	44
39	IPR016024 Armadillo-type fold	41	43	289	IPR001279 Beta-lactamase-like	8	9
40	IPR001849 Pleckstrin-like	40	143	290	IPR000560 Histidine acid phosphatase	8	40
41	IPR007087 Zinc finger, C2H2-type	39	422	291	IPR000331 Rap/ran-GAP	8	39
42	IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type	38	711	292	IPR000192 Aminotransferase, class V/Cysteine desulphurase	8	58
43	IPR000357 HEAT	38	262	293	IPR004031 PMP-22/EMP/MP20/Claudin	8	57
44	IPR000215 Protease inhibitor I4, serpin	38	230	294	IPR001487 Bromodomain	8	94
45	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	37	190	295	IPR001855 Beta defensin	8	8
46	IPR001664 Intermediate filament protein	37	329	296	IPR002259 Delayed-early response protein/equilibrative nucleoside transporter	8	49
47	IPR001092 Basic helix-loop-helix dimerisation region bHLH	36	171	297	IPR009886 HCaRG	8	8
48	IPR001304 C-type lectin	34	237	298	IPR006020 Phosphotyrosine interaction region	8	21
49	IPR000195 RabGAP/TBC	34	179	299	IPR000300 Inositol polyphosphate related phosphatase	8	53
50	IPR000436 Sushi/SCR/CCP	34	858	300	IPR001102 Transglutaminase, N-terminal	8	70
51	IPR000225 Armadillo	33	432	301	IPR001346 Interferon regulatory factor	7	46
52	IPR000169 Peptidase, cysteine peptidase active site	32	323	302	IPR003100 Argonaute and Dicer protein, PAZ	7	39
53	IPR001660 Sterile alpha motif SAM	32	358	303	IPR010569 Myotubularin-related	7	8
54	IPR003656 Zinc finger, BED-type predicted	32	929	304	IPR000494 EGF receptor, L domain	7	126
55	IPR000886 Endoplasmic reticulum, targeting sequence	32	283	305	IPR001507 Endoglin/CD105 antigen	7	46
56	IPR000299 Band 4.1, N-terminal	31	353	306	IPR006076 FAD dependent oxidoreductase	7	18
57	IPR000980 SH2 motif	31	267	307	IPR003316 Transcription factor E2F/dimerisation partner (TDP)	7	12
58	IPR000637 HMG-I and HMG-Y, DNA-binding	30	365	308	IPR000072 Platelet-derived growth factor (PDGF)	7	43
59	IPR001650 DNA/RNA helicase, C-terminal	30	204	309	IPR001494 Importin-beta, N-terminal	7	29
60	IPR000626 Ubiquitin	29	200	310	IPR000308 14-3-3 protein	7	77
61	IPR000608 Ubiquitin-conjugating enzyme, E2	29	131	311	IPR000469 G-protein alpha subunit, group 12	7	118
62	IPR003593 AAA+ ATPase, core	28	97	312	IPR002524 Cation efflux protein	7	9
63	IPR000571 Zinc finger, CCCH-type	28	167	313	IPR005821 Ion transport	7	10
64	IPR001125 Recoverin	28	417	314	IPR000756 Diacylglycerol kinase accessory region	7	85
65	IPR000330 SNF2-related	27	303	315	IPR003112 Olfactomedin-like	7	25
66	IPR000159 Ras-association	27	259	316	IPR004087 K Homology	7	65
67	IPR001757 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter	26	249	317	IPR007130 Diacylglycerol acyltransferase	7	7
68	IPR000873 AMP-dependent synthetase and ligase	26	86	318	IPR002190 MAGE protein	7	16
69	IPR000340 Protein-tyrosine phosphatase, dual specificity	26	202	319	IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal	7	28
70	IPR003439 ABC transporter-like	26	133	320	IPR003859 Metazoa galactosyltransferase	7	7
71	IPR001752 Kinesin, motor region	26	177	321	IPR000538 Link	7	231
72	IPR000301 CD9/CD37/CD63 antigen	26	169	322	IPR013216 Methyltransferase type 11	7	12
73	IPR000595 Cyclic nucleotide-binding	25	316	323	IPR002223 Proteinase inhibitor I2, Kunitz metazoa	7	87
74	IPR001623 Heat shock protein DnaJ, N-terminal	25	165	324	IPR002314 Aminoacyl-tRNA synthetase, class II (G, H, P and S)	7	53
75	IPR001005 SANT, DNA-binding	25	221	325	IPR000889 Glutathione peroxidase	7	39
76	IPR000342 Regulator of G protein signalling	24	217	326	IPR004182 GRAM	7	15
77	IPR000488 Death	24	348	327	IPR001089 Small chemokine, C-X-C	7	69
78	IPR003961 Fibronectin, type III	23	154	328	IPR001079 Galectin, galactose-binding lectin	7	36
79	IPR000073 Alpha/beta hydrolase fold-1	23	147	329	IPR011009 Protein kinase-like	7	9
80	IPR000727 Target SNARE coiled-coil region	22	117	330	IPR000836 Phosphoribosyltransferase	7	14
81	IPR000306 Zinc finger, FYVE-type	22	264	331	IPR008197 Whey acidic protein, 4-disulphide core	7	70
82	IPR000772 Ricin B lectin	22	156	332	IPR000555 Mov34/MPN/PAD-1	7	20
83	IPR000418 Ets	21	200	333	IPR001951 Histone H4	7	69
84	IPR001222 Zinc finger, TFIIS-type	21	699	334	IPR000463 Cytosolic fatty-acid binding	7	37
85	IPR001810 Cyclin-like F-box	21	88	335	IPR002108 Actin-binding, cofilin/tropomyosin type	7	31
86	IPR000629 RNA helicase, ATP-dependent, DEAD-box, conserved site	20	164	336	IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site	7	32
87	IPR001627 Semaphorin/CD100 antigen	20	250	337	IPR000162 GPCR, family 3, metabotropic glutamate receptor	7	173
88	IPR002035 von Willebrand factor, type A	20	185	338	IPR006652 Kelch repeat type 1	7	47
89	IPR001632 G-protein, beta subunit	20	500	339	IPR001932 Protein phosphatase 2C-related	7	21
90	IPR000832 GPCR, family 2, secretin-like	20	398	340	IPR000850 Adenylate kinase	7	43
91	IPR000483 Cysteine-rich flanking region, C-terminal	20	368	341	IPR000718 Peptidase M13, neprilysin	7	41
92	IPR000834 Peptidase M14, carboxypeptidase A	19	112	342	IPR001436 Alpha crystallin/Heat shock protein	7	61
93	IPR000003 Retinoid X receptor	19	454	343	IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core	7	14
94	IPR002073 3'5'-cyclic nucleotide phosphodiesterase	19	125	344	IPR002610 Peptidase S54, rhomboid	7	7
95	IPR008253 Marvel	19	35	345	IPR000562 Type II fibronectin, collagen-binding	7	186
96	IPR000014 PAS	19	277	346	IPR006651 Kelch	6	94
97	IPR001683 Phox-like	19	78	347	IPR004217 Zinc finger, Tim10/DDP-type	6	6
98	IPR001870 B302, (SPRY)-like	19	165	348	IPR007951 PMG	6	6
99	IPR003604 Zinc finger, U1-type	19	391	349	IPR000583 Glutamine amidotransferase, class-II	6	24
100	IPR000203 GPS	19	444	350	IPR001433 Oxidoreductase FAD/NAD(P)-binding	6	64
101	IPR000324 Vitamin D receptor	19	433	351	IPR001258 NHL repeat	6	68
102	IPR000408 Regulator of chromosome condensation, RCC1	19	311	352	IPR001778 Pollen allergen Poa pIX/Phl pVI, C-terminal	6	30
103	IPR004000 Actin/actin-like	18	98	353	IPR001736 Phospholipase D/Transphosphatidylase	6	27
104	IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular	18	96	354	IPR002052 N-6 adenine-specific DNA methylase, conserved site	6	29
105	IPR001766 Fork head transcription factor	18	121	355	IPR006662 Thioredoxin-related	6	33
106	IPR000157 Toll-Interleukin receptor	18	307	356	IPR001300 Peptidase C2, calpain	6	78
107	IPR016196 MFS general substrate transporter	18	22	357	IPR000434 Polycystic kidney disease type 1 protein	6	46
108	IPR000413 Integrins alpha chain	18	266	358	IPR006089 Acyl-CoA dehydrogenase, conserved site	6	43
109	IPR000585 Hemopexin	18	314	359	IPR000190 AT1 angiotensin II receptor	6	251
110	IPR001965 Zinc finger, PHD-type	18	110	360	IPR002909 Cell surface receptor IPT/TIG	6	30
111	IPR000767 Disease resistance protein	18	217	361	IPR001024 Lipoxygenase, LH2	6	121
112	IPR000863 Sulphotransferase	17	18	362	IPR000695 H+ transporting ATPase, proton pump	6	114
113	IPR000313 PWWP	17	202	363	IPR007593 Interferon-induced transmembrane protein	6	6
114	IPR000175 Sodium:neurotransmitter symporter	17	191	364	IPR002209 Heparin-binding growth factor/Fibroblast growth factor	6	55
115	IPR001675 Glycosyl transferase, family 29	17	29	365	IPR004046 Glutathione S-transferase, C-terminal	6	13
116	IPR000910 High mobility group box, HMG1/HMG2	17	79	366	IPR001094 Flavodoxin-like	6	78
117	IPR001496 SOCS protein, C-terminal	17	265	367	IPR000409 Beige/BEACH	6	65
118	IPR007114 Major facilitator superfamily	16	51	368	IPR001305 Heat shock protein DnaJ, cysteine-rich region	6	51
119	IPR001202 WW/Rsp5/WWP	16	162	369	IPR003034 DNA-binding SAP	6	30
120	IPR001140 ABC transporter, transmembrane region	16	175	370	IPR001251 Cellular retinaldehyde-binding/triple function, C-terminal	6	26
121	IPR001991 Sodium:dicarboxylate symporter	16	160	371	IPR002495 Glycosyl transferase, family 8	6	6
122	IPR000253 Forkhead-associated	16	129	372	IPR005301 Mob1/phocein	6	12
123	IPR003006 Immunoglobulin/major histocompatibility complex, conserved site	16	208	373	IPR001873 Na+ channel, amiloride-sensitive	6	61
124	IPR000421 Coagulation factor 5/8 type, C-terminal	16	337	374	IPR008972 Cupredoxin	6	28
125	IPR013026 Tetratricopeptide region	16	46	375	IPR001129 Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG)	6	22
126	IPR000449 Ubiquitin-associated/translation elongation factor EF1B, N-terminal	16	145	376	IPR000239 GPCR kinase	6	90
127	IPR000859 CUB	16	258	377	IPR003533 Doublecortin	6	28
128	IPR000558 Histone H2B	15	134	378	IPR013787 S100/CaBP-9k-type, calcium binding, subdomain	6	6
129	IPR005816 Secreted growth factor Wnt protein	15	144	379	IPR001365 Adenosine/AMP deaminase	6	15
130	IPR001320 Ionotropic glutamate receptor	15	93	380	IPR001310 Histidine triad (HIT) protein	6	27
131	IPR003599 Immunoglobulin subtype	15	45	381	IPR001958 Tetracycline resistance protein, TetA	6	41
132	IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site	15	132	382	IPR005076 Glycosyl transferase, family 6	6	6
133	IPR001073 Complement C1q protein	15	140	383	IPR002893 Zinc finger, MYND-type	6	39
134	IPR001190 Speract/scavenger receptor	15	289	384	IPR003117 cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta	6	16
135	IPR000086 NUDIX hydrolase, core	15	88	385	IPR000034 Laminin B	6	573
136	IPR001594 Zinc finger, DHHC-type	15	43	386	IPR003663 Sugar transporter	6	55
137	IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit	15	191	387	IPR001026 Epsin, N-terminal	6	39
138	IPR001148 Carbonic anhydrase, eukaryotic	15	55	388	IPR002423 Chaperonin Cpn60/TCP-1	6	18
139	IPR001214 SET	15	135	389	IPR000375 Dynamin central region	6	55
140	IPR002394 Nicotinic acetylcholine receptor, N-terminal	15	171	390	IPR007632 Protein of unknown function DUF590	6	7
141	IPR001368 TNFR/CD27/30/40/95 cysteine-rich region	15	251	391	IPR000975 Interleukin-1	6	106
142	IPR001526 CD59 antigen	14	26	392	IPR000058 Zinc finger, AN1-type	6	28
143	IPR001023 Heat shock protein Hsp70	14	133	393	IPR001429 P2X purinoreceptor	6	70
144	IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase	14	44	394	IPR000007 Tubby, C-terminal	6	77
145	IPR000248 Angiotensin II receptor	14	510	395	IPR000956 Stathmin	6	37
146	IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding	14	185	396	IPR006055 Exonuclease	6	18
147	IPR000716 Thyroglobulin type-1	14	172	397	IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype	6	28
148	IPR000717 Proteasome component region PCI	14	30	398	IPR001678 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p	6	11
149	IPR001163 Like-Sm ribonucleoprotein, core	14	43	399	IPR002014 VHS	6	44
150	IPR000403 Phosphatidylinositol 3- and 4-kinase, catalytic	14	120	400	IPR008380 HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase	6	9
151	IPR001715 Calponin-like actin-binding	14	81	401	IPR001017 Dehydrogenase, E1 component	6	11
152	IPR001039 MHC class I, alpha chain, alpha1 and alpha2	14	104	402	IPR001239 Proteinase inhibitor I1, Kazal metazoa	6	78
153	IPR000233 Cadherin cytoplasmic region	14	334	403	IPR002293 Amino acid/polyamine transporter I	6	12
154	IPR005135 Endonuclease/exonuclease/phosphatase	14	59	404	IPR008011 Complex 1 LYR protein	6	6
155	IPR000010 Proteinase inhibitor I25, cystatin	14	47	405	IPR005522 Inositol polyphosphate kinase	6	6
156	IPR000209 Peptidase S8 and S53, subtilisin, kexin, sedolisin	14	183	406	IPR007052 CS domain	6	24
157	IPR000500 Connexins	13	130	407	IPR012496 TMC	6	6
158	IPR000182 GCN5-related N-acetyltransferase	13	68	408	IPR003072 Orphan nuclear receptor, NOR1 type	6	17
159	IPR001124 Lipid-binding serum glycoprotein	13	41	409	IPR002091 Aromatic amino acid permease	6	21
160	IPR000480 Glutelin	13	134	410	IPR008661 L6 membrane	6	6
161	IPR001194 DENN	13	97	411	IPR000974 Glycoside hydrolase, family 22, lysozyme	6	69
162	IPR009053 Prefoldin	13	19	412	IPR002129 Pyridoxal phosphate-dependent decarboxylase	6	31
163	IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase	13	109	413	IPR002087 Anti-proliferative protein	5	35
164	IPR001509 NAD-dependent epimerase/dehydratase	13	79	414	IPR011032 GroES-like	5	15
165	IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit	13	227	415	IPR001978 Troponin	5	5
166	IPR000795 Protein synthesis factor, GTP-binding	13	136	416	IPR007109 Brix	5	10
167	IPR000164 Histone H3	13	124	417	IPR000098 Interleukin-10	5	18
168	IPR000827 Small chemokine, C-C group, conserved site	13	84	418	IPR016181 Acyl-CoA N-acyltransferase	5	6
169	IPR001878 Zinc finger, CCHC-type	13	84	419	IPR001553 RecA bacterial DNA recombination	5	28
170	IPR000917 Sulphatase	13	43	420	IPR008962 PapD-like	5	6
171	IPR000566 Lipocalin-related protein and Bos/Can/Equ allergen	13	180	421	IPR003531 Short hematopoietin receptor, family 1, conserved site	5	23
172	IPR013057 Amino acid transporter, transmembrane	12	12	422	IPR002172 Low density lipoprotein-receptor, class A, cysteine-rich	5	61
173	IPR000467 D111/G-patch	12	58	423	IPR004825 Insulin/IGF/relaxin	5	16
174	IPR001064 Beta and gamma crystallin	12	136	424	IPR006634 TRAM, LAG1 and CLN8 homology	5	12
175	IPR000648 Oxysterol-binding protein	12	46	425	IPR010622 FAST kinase leucine-rich	5	14
176	IPR007110 Immunoglobulin-like	12	17	426	IPR010345 Interleukin-17	5	5
177	IPR000425 Major intrinsic protein	12	92	427	IPR002076 GNS1/SUR4 membrane protein	5	12
178	IPR000837 Fos transforming protein	12	110	428	IPR000764 Uridine kinase	5	32
179	IPR002494 Keratin, high sulphur B2 protein	12	16	429	IPR001898 Sodium/sulphate symporter	5	9
180	IPR000158 Cell division protein FtsZ, N-terminal	12	539	430	IPR008331 Ferritin and Dps	5	19
181	IPR000033 Low-density lipoprotein receptor, YWTD repeat	12	1069	431	IPR001876 Zinc finger, RanBP2-type	5	18
182	IPR001589 Actinin-type, actin-binding, conserved site	12	252	432	IPR004686 Tricarboxylate/iron carrier	5	7
183	IPR004367 Cyclin, C-terminal	12	64	433	IPR000582 Acyl-CoA-binding protein, ACBP	5	41
184	IPR003091 Voltage-dependent potassium channel	12	196	434	IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45	5	5
185	IPR000679 Zinc finger, GATA-type	12	182	435	IPR000536 Nuclear hormone receptor, ligand-binding, core	5	100
186	IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II	11	213	436	IPR000941 Enolase	5	39
187	IPR001270 Chaperonin clpA/B	11	76	437	IPR002155 Thiolase	5	38
188	IPR001751 S100/CaBP-9k-type, calcium binding	11	67	438	IPR003267 Small proline-rich	5	16
189	IPR002917 GTP-binding protein, HSR1-related	11	44	439	IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase	5	11
190	IPR001315 Caspase Recruitment	11	93	440	IPR002007 Haem peroxidase, animal	5	45
191	IPR004344 Tubulin-tyrosine ligase	11	13	441	IPR003000 NAD-dependent histone deacetylase, silent information regulator Sir2	5	13
192	IPR000953 Chromo domain	11	90	442	IPR001606 AT-rich interaction region	5	62
193	IPR000712 Apoptosis regulator Bcl-2, BH	11	95	443	IPR001003 MHC class II, alpha chain, N-terminal	5	34
194	IPR000348 emp24/gp25L/p24	11	49	444	IPR004877 Cytochrome b561	5	16
195	IPR001007 von Willebrand factor, type C	11	265	445	IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site	5	19
196	IPR000337 GPCR, family 3	11	101	446	IPR000451 NF-kappa-B/Rel/dorsal	5	93
197	IPR001164 Arf GTPase activating protein	11	106	447	IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase	5	7
198	IPR000217 Tubulin	11	320	448	IPR000426 Proteasome alpha-subunit, conserved site	5	10
199	IPR000038 Cell division/GTP binding protein	11	37	449	IPR011701 Major facilitator superfamily MFS-1	5	11
200	IPR001357 BRCT	11	142	450	IPR000011 Ubiquitin-activating enzyme, E1	5	41
201	IPR000001 Kringle	11	254	451	IPR007084 BRICHOS	5	10
202	IPR000731 Sterol-sensing 5TM box	11	35	452	IPR001132 SMAD domain, Dwarfin-type	5	36
203	IPR001111 Transforming growth factor beta (TGFb), N-terminal	11	80	453	IPR000738 WHEP-TRS	5	64
204	IPR000644 Cystathionine beta-synthase, core	11	113	454	IPR003137 Protease-associated PA	5	13
205	IPR001293 Zinc finger, TRAF-type	11	138	455	IPR004841 Amino acid permease-associated region	5	5
206	IPR002957 Keratin, type I	11	66	456	IPR007603 Protein of unknown function DUF580	5	5
207	IPR000024 Frizzled cysteine-rich domain	11	164	457	IPR000381 Inhibin, beta B subunit	5	62
208	IPR000270 Octicosapeptide/Phox/Bem1p	11	115	458	IPR003010 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase	5	16
209	IPR004827 Basic-leucine zipper (bZIP) transcription factor	11	28	459	IPR001799 Ephrin	5	32
210	IPR001699 Transcription factor, T-box	11	130	460	IPR002589 Appr-1-p processing	5	18
211	IPR001159 Double-stranded RNA binding	11	65	461	IPR000402 ATPase, P-type cation exchange, beta subunit	5	14
212	IPR001464 Annexin	11	245	462	IPR013568 SEFIR	5	5
213	IPR000261 EPS15 homology (EH)	11	103	463	IPR001619 Sec1-like protein	5	14
214	IPR002119 Histone H2A	11	95	464	IPR005176 Protein of unknown function DUF298	5	5
215	IPR001199 Cytochrome b5	11	70	465	IPR007053 NC	5	5
216	IPR000095 PAK-box/P21-Rho-binding	11	108	466	IPR001392 Clathrin adaptor, mu subunit	5	47
217	IPR001395 Aldo/keto reductase	11	86	467	IPR000697 EVH1	5	17
218	IPR001839 Transforming growth factor beta	11	62	468	IPR004273 Dynein heavy chain	5	8
219	IPR015590 Aldehyde dehydrogenase	11	45	469	IPR005814 Aminotransferase class-III	5	16
220	IPR011046 WD40 repeat-like	11	16	470	IPR000174 Interleukin-8 receptor	5	196
221	IPR000286 Histone deacetylase superfamily	10	65	471	IPR001759 Pentaxin	5	46
222	IPR007237 CD20/IgE Fc receptor beta subunit	10	11	472	IPR001404 Heat shock protein Hsp90	5	43
223	IPR006594 LisH dimerisation motif	10	40	473	IPR001353 20S proteasome, A and B subunits	5	8
224	IPR000433 Zinc finger, ZZ-type	10	131	474	IPR004012 RUN	5	13
225	IPR002130 Peptidyl-prolyl cis-trans isomerase, cyclophilin-type	10	89	475	IPR003092 Potassium channel, two pore-domain, TASK	5	67
226	IPR001770 G-protein, gamma subunit	10	60	476	IPR002946 Intracellular chloride channel	5	31
227	IPR001811 Small chemokine, interleukin-8-like	10	36	477	IPR004455 NADP oxidoreductase, coenzyme F420-dependent	5	11
228	IPR001461 Peptidase A1	10	78	478	IPR001173 Glycosyl transferase, family 2	5	5
229	IPR003347 Transcription factor jumonji/aspartyl beta-hydroxylase	10	28	479	IPR006612 Zinc finger, C2CH-type	5	16
230	IPR001309 Peptidase C14, ICE, catalytic subunit p20	10	115	480	IPR012461 Protein of unknown function DUF1669	5	5
231	IPR003309 Transcriptional regulator SCAN	10	245	481	IPR000542 Acyltransferase ChoActase/COT/CPT	5	14
232	IPR000082 SEA	10	232	482	IPR004345 TB2/DP1 and HVA22 related protein	5	5
233	IPR000904 SEC7-like	10	61	483	IPR001345 Phosphoglycerate/bisphosphoglycerate mutase	5	36
234	IPR003597 Immunoglobulin C1-set	10	60	484	IPR002937 Amine oxidase	5	8
235	IPR000135 High mobility group box, HMG1/HMG2, subgroup	10	144	485	IPR000009 Protein phosphatase 2A, regulatory subunit PR55	5	114
236	IPR002123 Phospholipid/glycerol acyltransferase	10	23	486	IPR001312 Hexokinase	5	57
237	IPR006025 Peptidase M, neutral zinc metallopeptidases, zinc-binding site	10	41	487	IPR001247 Exoribonuclease, phosphorolytic domain 1	5	19
238	IPR004299 Membrane bound O-acyl transferase, MBOAT	9	9	488	IPR005819 Histone H5	5	19
239	IPR000577 Carbohydrate kinase, FGGY	9	880	489	IPR001156 Peptidase S60, transferrin lactoferrin	5	70
240	IPR000971 Globin, subset	9	124	490	IPR000664 Lethal(2) giant larvae protein	5	71
241	IPR000333 Activin type II receptor	9	110	491	IPR000938 Cytoskeleton-associated protein, CAP-Gly	5	34
242	IPR001283 Allergen V5/Tpx-1 related	9	78	492	IPR000640 Translation elongation factor EFG/EF2, C-terminal	5	52
243	IPR002229 Blood group Rhesus C/E and D polypeptide	9	81	493	IPR007604 CP2 transcription factor	5	7
244	IPR003689 Zinc/iron permease	9	9	494	IPR007677 DFNA5 protein	5	5
245	IPR001734 Na+/solute symporter	9	30	495	IPR000061 SWAP/Surp	5	40
246	IPR004853 Protein of unknown function DUF250	9	17	496	IPR000866 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen	5	16
247	IPR000817 Prion protein	9	109	497	IPR000116 High mobility group proteins HMG-I and HMG-Y	5	62
248	IPR001564 Nucleoside diphosphate kinase, core	9	70	498	IPR001590 Peptidase M12B, ADAM/reprolysin	5	39
249	IPR001060 Cdc15/Fes/CIP4	9	73	499	IPR003653 Peptidase C48, SUMO/Sentrin/Ubl1	5	12
250	IPR000601 PKD	9	55	500	IPR000432 DNA mismatch repair protein MutS, C-terminal	5	85

View top 40 InterPro hits

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