Top 500 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000276 Rhodopsin-like GPCR superfamily	578	7888	251	IPR013106 Immunoglobulin V-set	9	9
2	IPR000694 Proline-rich region	494	4033	252	IPR002223 Proteinase inhibitor I2, Kunitz metazoa	9	109
3	IPR000719 Protein kinase	300	3141	253	IPR003173 Transcriptional coactivator p15	9	9
4	IPR003596 Immunoglobulin V-set, subgroup	192	1820	254	IPR001279 Beta-lactamase-like	9	12
5	IPR001909 KRAB box	158	2752	255	IPR000331 Rap/ran-GAP	9	17
6	IPR000504 RNA-binding region RNP-1 (RNA recognition motif)	151	919	256	IPR001089 Small chemokine, C-X-C	9	74
7	IPR001680 WD-40 repeat	149	1945	257	IPR001079 Galectin, galactose-binding lectin	9	24
8	IPR000008 C2 calcium-dependent membrane targeting	91	1095	258	IPR002049 EGF-like, laminin	9	250
9	IPR000210 BTB	90	1479	259	IPR004827 Basic-leucine zipper (bZIP) transcription factor	9	20
10	IPR001781 LIM, zinc-binding	88	2840	260	IPR002075 Nuclear transport factor 2	9	21
11	IPR000533 Tropomyosin	85	545	261	IPR003597 Immunoglobulin C1-set	9	34
12	IPR001841 Zinc finger, RING-type	83	391	262	IPR001012 UBX	9	26
13	IPR001611 Leucine-rich repeat	79	851	263	IPR000555 Mov34/MPN/PAD-1	9	19
14	IPR002110 Ankyrin	78	1103	264	IPR001199 Cytochrome b5	9	45
15	IPR001806 Ras GTPase	77	779	265	IPR000679 Zinc finger, GATA-type	9	171
16	IPR002048 Calcium-binding EF-hand	73	465	266	IPR000804 Clathrin adaptor complex, small chain	9	16
17	IPR000048 IQ calmodulin-binding region	66	966	267	IPR004299 Membrane bound O-acyl transferase, MBOAT	8	8
18	IPR000047 Helix-turn-helix motif, lambda-like repressor	64	723	268	IPR006651 Kelch motif	8	127
19	IPR000152 Aspartic acid and asparagine hydroxylation site	63	3652	269	IPR004217 Zinc finger, Tim10/DDP-type	8	8
20	IPR001440 Tetratricopeptide TPR_1	59	1047	270	IPR007237 CD20/IgE Fc receptor beta subunit	8	8
21	IPR000104 Antifreeze protein, type I	57	525	271	IPR000494 EGF receptor, L domain	8	137
22	IPR003598 Immunoglobulin subtype 2	57	635	272	IPR001507 Endoglin/CD105 antigen	8	40
23	IPR000742 EGF-like, type 3	49	1394	273	IPR006662 Thioredoxin-related	8	30
24	IPR000198 RhoGAP	49	317	274	IPR000434 Polycystic kidney disease type 1 protein	8	83
25	IPR001128 Cytochrome P450	48	831	275	IPR003599 Immunoglobulin subtype	8	19
26	IPR000219 DH	48	589	276	IPR002524 Cation efflux protein	8	15
27	IPR007087 Zinc finger, C2H2-type	48	489	277	IPR000756 Diacylglycerol kinase accessory region	8	115
28	IPR001356 Homeobox	47	260	278	IPR003112 Olfactomedin-like	8	27
29	IPR001304 C-type lectin	45	303	279	IPR013149 Alcohol dehydrogenase, zinc-binding	8	12
30	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	45	283	280	IPR000817 Prion protein	8	92
31	IPR007109 Brix	44	86	281	IPR001290 Poly(ADP-ribose) polymerase, catalytic region	8	75
32	IPR001664 Intermediate filament protein	43	280	282	IPR003267 Small proline-rich	8	30
33	IPR003006 Immunoglobulin/major histocompatibility complex	43	334	283	IPR002350 Proteinase inhibitor I1, Kazal	8	30
34	IPR000884 Thrombospondin, type I	42	597	284	IPR007130 Diacylglycerol acyltransferase	8	8
35	IPR007086 Zinc finger, C2H2-subtype	42	1048	285	IPR001564 Nucleoside diphosphate kinase	8	56
36	IPR000315 Zinc finger, B-box	42	548	286	IPR001461 Peptidase A1	8	51
37	IPR001452 Src homology-3	41	413	287	IPR001211 Phospholipase A2	8	58
38	IPR001478 PDZ/DHR/GLGF	40	327	288	IPR002077 Ca2+ channel, alpha subunit	8	106
39	IPR001993 Mitochondrial substrate carrier	40	383	289	IPR001753 Enoyl-CoA hydratase/isomerase	8	16
40	IPR001092 Basic helix-loop-helix dimerisation region bHLH	40	147	290	IPR000403 Phosphatidylinositol 3- and 4-kinase, catalytic	8	52
41	IPR001849 Pleckstrin-like	39	150	291	IPR001509 NAD-dependent epimerase/dehydratase	8	37
42	IPR000108 Neutrophil cytosol factor 2	39	778	292	IPR001958 Tetracycline resistance protein	8	48
43	IPR000980 SH2 motif	39	306	293	IPR002893 Zinc finger, MYND-type	8	40
44	IPR000357 HEAT	37	188	294	IPR001169 Integrin beta, C-terminal	8	200
45	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	35	141	295	IPR002017 Spectrin repeat	8	12
46	IPR002198 Short-chain dehydrogenase/reductase SDR	35	348	296	IPR005135 Endonuclease/exonuclease/phosphatase	8	17
47	IPR000608 Ubiquitin-conjugating enzyme, E2	35	123	297	IPR001392 Clathrin adaptor complex, medium chain	8	30
48	IPR001650 Helicase, C-terminal	35	179	298	IPR004273 Dynein heavy chain	8	10
49	IPR002126 Cadherin	35	836	299	IPR007632 Protein of unknown function DUF590	8	8
50	IPR000215 Proteinase inhibitor I4, serpin	35	199	300	IPR001404 Heat shock protein Hsp90	8	61
51	IPR000436 Sushi/SCR/CCP	35	680	301	IPR000975 Interleukin-1	8	82
52	IPR000225 Armadillo	35	381	302	IPR004012 RUN	8	19
53	IPR000242 Tyrosine specific protein phosphatase	34	631	303	IPR001951 Histone H4	8	44
54	IPR000169 Peptidase, cysteine peptidase active site	34	281	304	IPR000010 Proteinase inhibitor I25, cystatin	8	46
55	IPR000306 Zinc finger, FYVE-type	33	537	305	IPR000243 Peptidase T1A, proteasome beta-subunit	8	29
56	IPR000195 RabGAP/TBC	32	124	306	IPR001590 Peptidase M12B, ADAM/reprolysin	8	62
57	IPR000886 Endoplasmic reticulum targeting sequence	32	185	307	IPR000223 Peptidase S26A, signal peptidase I	8	57
58	IPR000299 Band 4.1	31	318	308	IPR000300 Inositol polyphosphate related phosphatase	8	34
59	IPR000079 High mobility group protein HMG14 and HMG17	31	199	309	IPR013057 Amino acid transporter, transmembrane	7	7
60	IPR001660 Sterile alpha motif SAM	31	300	310	IPR000558 Histone H2B	7	56
61	IPR000637 HMG-I and HMG-Y, DNA-binding	30	310	311	IPR001208 MCM	7	75
62	IPR000372 Leucine-rich repeat, cysteine-rich flanking region, N-terminal	30	625	312	IPR001427 Pancreatic ribonuclease	7	36
63	IPR000449 Ubiquitin-associated/Translation elongation factor EF1B, N-terminal	30	250	313	IPR002917 GTP-binding protein, HSR1-related	7	28
64	IPR000873 AMP-dependent synthetase and ligase	29	107	314	IPR006594 Lissencephaly type-1-like homology motif	7	23
65	IPR000571 Zinc finger, CCCH-type	29	144	315	IPR000333 Activin type II receptor	7	77
66	IPR000135 High mobility group box HMG1 and HMG2	29	278	316	IPR003316 Transcription factor E2F/dimerisation partner (TDP)	7	9
67	IPR000408 Regulator of chromosome condensation, RCC1	28	335	317	IPR000308 14-3-3 protein	7	49
68	IPR001005 Myb, DNA-binding	28	164	318	IPR000994 Peptidase M24, catalytic core	7	30
69	IPR003656 Zinc finger, BED-type predicted	26	701	319	IPR010370 Transcription elongation factor A, SII-related	7	7
70	IPR000330 SNF2-related	25	185	320	IPR002114 Phosphotransferase system, HPr serine phosphorylation site	7	103
71	IPR003593 AAA+ ATPase, core	25	63	321	IPR000601 PKD	7	37
72	IPR000159 RA	25	218	322	IPR002553 Adaptin, N-terminal	7	16
73	IPR001752 Kinesin, motor region	25	161	323	IPR006680 Amidohydrolase 1	7	12
74	IPR001623 Heat shock protein DnaJ, N-terminal	25	149	324	IPR006575 RWD	7	25
75	IPR000014 PAS	24	294	325	IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase	7	11
76	IPR002035 von Willebrand factor, type A	24	150	326	IPR007084 BRICHOS	7	7
77	IPR001757 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter	24	238	327	IPR001873 Na+ channel, amiloride-sensitive	7	67
78	IPR000340 Dual specificity protein phosphatase	24	140	328	IPR000158 Cell division protein FtsZ	7	294
79	IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit	23	294	329	IPR001293 Zinc finger, TRAF-type	7	44
80	IPR000324 Vitamin D receptor	23	486	330	IPR005123 2OG-Fe(II) oxygenase	7	21
81	IPR000585 Hemopexin	23	331	331	IPR000889 Glutathione peroxidase	7	36
82	IPR000834 Peptidase M14, carboxypeptidase A	22	139	332	IPR000270 Octicosapeptide/Phox/Bem1p	7	60
83	IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding	22	193	333	IPR001223 Glycoside hydrolase, family 18, catalytic domain	7	18
84	IPR000772 Ricin B lectin	22	151	334	IPR000697 EVH1	7	19
85	IPR001715 Calponin-like actin-binding	22	94	335	IPR001759 Pentaxin	7	65
86	IPR000301 CD9/CD37/CD63 antigen	22	105	336	IPR001152 Thymosin beta-4	7	14
87	IPR000483 Cysteine-rich flanking region, C-terminal	22	388	337	IPR004031 PMP-22/EMP/MP20 and claudin	7	38
88	IPR002086 Aldehyde dehydrogenase	22	78	338	IPR006055 Exonuclease	7	15
89	IPR000626 Ubiquitin	21	102	339	IPR000183 Orn/DAP/Arg decarboxylase 2	7	86
90	IPR000342 Regulator of G protein signalling	21	173	340	IPR001678 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p	7	11
91	IPR003961 Fibronectin, type III	21	118	341	IPR002366 Defensin propeptide	7	11
92	IPR001895 Guanine-nucleotide dissociation stimulator CDC25	21	60	342	IPR001239 Proteinase inhibitor I1, Kazal metazoa	7	84
93	IPR001632 G-protein, beta subunit	20	467	343	IPR001247 Exoribonuclease	7	17
94	IPR003604 Zinc finger, U1-type	20	340	344	IPR003323 Ovarian tumour, otubain	7	12
95	IPR000086 NUDIX hydrolase	20	76	345	IPR000116 High mobility group proteins HMG-I and HMG-Y	7	50
96	IPR000595 Cyclic nucleotide-binding	20	232	346	IPR008011 Complex 1 LYR protein	7	7
97	IPR001810 Cyclin-like F-box	20	90	347	IPR007052 CS	7	14
98	IPR000418 Ets	19	144	348	IPR006025 Peptidase M, neutral zinc metallopeptidases, zinc-binding site	7	13
99	IPR001202 WW/Rsp5/WWP	19	154	349	IPR012496 TMC	7	7
100	IPR000175 Sodium:neurotransmitter symporter	19	193	350	IPR002164 Nucleosome assembly protein (NAP)	7	7
101	IPR000203 GPS	19	285	351	IPR001932 Protein phosphatase 2C-related	7	17
102	IPR013026 Tetratricopeptide region	19	53	352	IPR001071 Cellular retinaldehyde binding/alpha-tocopherol transport	7	57
103	IPR000767 Disease resistance protein	19	222	353	IPR006020 Phosphotyrosine interaction region	7	15
104	IPR004843 Metallophosphoesterase	18	98	354	IPR002129 Pyridoxal-dependent decarboxylase	7	32
105	IPR000629 ATP-dependent helicase, DEAD-box	18	104	355	IPR001236 Lactate/malate dehydrogenase	7	41
106	IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular	18	45	356	IPR002394 Nicotinic acetylcholine receptor	7	74
107	IPR001870 B302, (SPRY)-like	18	130	357	IPR000911 Ribosomal protein L11	6	16
108	IPR000832 GPCR, family 2, secretin-like	18	327	358	IPR006816 Engulfment and cell motility, ELM	6	6
109	IPR000421 Coagulation factor 5/8 type, C-terminal	18	330	359	IPR001270 Chaperonin clpA/B	6	26
110	IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit	18	351	360	IPR003100 Argonaute and Dicer protein, PAZ	6	24
111	IPR000859 CUB	18	242	361	IPR000583 Glutamine amidotransferase, class-II	6	20
112	IPR004000 Actin/actin-like	17	102	362	IPR000005 Helix-turn-helix, AraC type	6	11128
113	IPR000248 Angiotensin II receptor	17	542	363	IPR013032 EGF-like region	6	10
114	IPR002073 3'5'-cyclic nucleotide phosphodiesterase	17	135	364	IPR001494 Importin-beta, N-terminal	6	15
115	IPR001766 Fork head transcription factor	17	100	365	IPR002052 N-6 Adenine-specific DNA methylase	6	68
116	IPR001683 Phox-like	17	56	366	IPR000469 G-protein alpha subunit, group 12	6	112
117	IPR002209 Heparin-binding growth factor/Fibroblast growth factor	17	133	367	IPR000407 Nucleoside phosphatase GDA1/CD39	6	8
118	IPR001140 ABC transporter, transmembrane region	17	92	368	IPR001300 Peptidase C2, calpain	6	48
119	IPR001190 Speract/scavenger receptor	17	281	369	IPR000348 emp24/gp25L/p24	6	24
120	IPR001991 Sodium:dicarboxylate symporter	17	121	370	IPR001553 RecA bacterial DNA recombination	6	13
121	IPR001039 MHC class I, alpha chain, alpha1 and alpha2	17	99	371	IPR004254 Hly-III related proteins	6	8
122	IPR000413 Integrins alpha chain	17	240	372	IPR000190 AT1 angiotensin II receptor	6	236
123	IPR001675 Glycosyl transferase, family 29	17	26	373	IPR002076 GNS1/SUR4 membrane protein	6	13
124	IPR001965 Zinc finger, PHD-type	17	75	374	IPR000764 Uridine kinase	6	39
125	IPR002119 Histone H2A	17	126	375	IPR002909 Cell surface receptor IPT/TIG	6	53
126	IPR000863 Sulfotransferase	16	18	376	IPR004045 Glutathione S-transferase, N-terminal	6	16
127	IPR001320 Ionotropic glutamate receptor	16	92	377	IPR000695 H+ transporting ATPase, proton pump	6	118
128	IPR001627 Semaphorin/CD100 antigen	16	85	378	IPR000651 Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal	6	52
129	IPR001007 von Willebrand factor, type C	16	176	379	IPR001360 Glycoside hydrolase, family 1	6	33
130	IPR004087 KH	16	103	380	IPR000023 Phosphofructokinase	6	107
131	IPR000313 PWWP	16	157	381	IPR001734 Na+/solute symporter	6	24
132	IPR003439 ABC transporter related	16	68	382	IPR001862 Membrane attack complex component/perforin/complement C9	6	13
133	IPR001214 SET	16	173	383	IPR001107 Band 7 protein	6	40
134	IPR000073 Alpha/beta hydrolase fold-1	16	79	384	IPR000409 Beige/BEACH	6	74
135	IPR000253 Forkhead-associated	15	101	385	IPR010625 CHCH	6	6
136	IPR000488 Death	15	209	386	IPR003034 DNA-binding SAP	6	23
137	IPR001589 Actin-binding, actinin-type	15	348	387	IPR005301 Mob1/phocein	6	7
138	IPR000233 Cadherin cytoplasmic region	15	345	388	IPR001176 1-aminocyclopropane-1-carboxylate synthase	6	28
139	IPR000095 PAK-box/P21-Rho-binding	15	135	389	IPR006977 Yip1 domain	6	6
140	IPR001125 Recoverin	15	203	390	IPR000538 Link	6	123
141	IPR000209 Peptidase S8 and S53, subtilisin, kexin, sedolisin	15	149	391	IPR001132 MAD homology 2, Dwarfin-type	6	22
142	IPR001368 TNFR/CD27/30/40/95 cysteine-rich region	15	116	392	IPR000089 Biotin/lipoyl attachment	6	42
143	IPR000727 Target SNARE coiled-coil region	14	57	393	IPR013216 Methyltransferase type 11	6	9
144	IPR000157 Toll-Interleukin receptor	14	248	394	IPR001388 Synaptobrevin	6	31
145	IPR001770 G-protein, gamma subunit	14	72	395	IPR004841 Amino acid permease-associated region	6	6
146	IPR001811 Small chemokine, interleukin-8-like	14	39	396	IPR002314 tRNA synthetase, class II (G, H, P and S)	6	36
147	IPR001164 Arf GTPase activating protein	14	134	397	IPR002961 Tumour necrosis factor c/lymphotoxin-beta	6	72
148	IPR003573 Interleukin-6/G-CSF/MGF	14	99	398	IPR000322 Glycoside hydrolase, family 31	6	21
149	IPR001222 Transcription factor TFIIS	14	703	399	IPR001515 Ribosomal protein L32e	6	8
150	IPR000480 Glutelin	14	105	400	IPR001799 Ephrin	6	35
151	IPR001111 Transforming growth factor beta (TGFb), N-terminal	14	106	401	IPR000218 Ribosomal protein L14b/L23e	6	7
152	IPR001073 Complement C1q protein	14	86	402	IPR001310 Histidine triad (HIT) protein	6	22
153	IPR001309 Caspase, p20 subunit	14	154	403	IPR001619 Sec1-like protein	6	6
154	IPR000033 Low-density lipoprotein receptor, YWTD repeat	14	1073	404	IPR000034 Laminin B	6	339
155	IPR001163 Like-Sm ribonucleoprotein, core	14	28	405	IPR007053 NC	6	6
156	IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase	14	84	406	IPR000836 Phosphoribosyltransferase	6	16
157	IPR001148 Carbonic anhydrase, eukaryotic	14	20	407	IPR001353 20S proteasome, A and B subunits	6	6
158	IPR000910 HMG1/2 (high mobility group) box	14	62	408	IPR003409 MORN motif	6	59
159	IPR000569 HECT	14	111	409	IPR000058 Zinc finger, AN1-type	6	24
160	IPR001496 SOCS protein, C-terminal	14	241	410	IPR000956 Stathmin	6	32
161	IPR001526 CD59 antigen	13	21	411	IPR001345 Phosphoglycerate/bisphosphoglycerate mutase	6	31
162	IPR001751 S100/CaBP-9k-type, calcium binding	13	74	412	IPR002937 Amine oxidase	6	11
163	IPR000326 Phosphoesterase, PA-phosphatase related	13	23	413	IPR000222 Protein phosphatase 2C	6	22
164	IPR000953 Chromo	13	110	414	IPR000162 Metabotropic glutamate receptor	6	148
165	IPR008253 Marvel	13	16	415	IPR005819 Histone H5	6	19
166	IPR000837 Fos transforming protein	13	128	416	IPR001599 Alpha-2-macroglobulin	6	37
167	IPR000024 Frizzled CRD region	13	165	417	IPR003594 ATP-binding region, ATPase-like	6	26
168	IPR000463 Cytosolic fatty-acid binding	13	48	418	IPR000640 Translation elongation factor EFG/EF2, C-terminal	6	42
169	IPR000261 EPS15 homology (EH)	13	158	419	IPR007604 CP2 transcription factor	6	6
170	IPR004367 Cyclin, C-terminal	13	44	420	IPR007677 DFNA5 protein	6	6
171	IPR000917 Sulfatase	13	27	421	IPR006652 Kelch repeat	6	33
172	IPR001395 Aldo/keto reductase	13	81	422	IPR007863 Peptidase M16, C-terminal	6	13
173	IPR000182 GCN5-related N-acetyltransferase	12	29	423	IPR003091 Voltage-dependent potassium channel	6	69
174	IPR007114 Major facilitator superfamily	12	24	424	IPR003653 Peptidase C48, SUMO/Sentrin/Ubl1	6	12
175	IPR000003 Retinoid X receptor	12	280	425	IPR001375 Peptidase S9, prolyl oligopeptidase active site region	6	29
176	IPR002130 Peptidyl-prolyl cis-trans isomerase, cyclophilin-type	12	71	426	IPR002913 Lipid-binding START	6	16
177	IPR000517 Ribosomal protein L30	12	40	427	IPR004241 Light chain 3 (LC3)	6	6
178	IPR000038 Cell division/GTP binding protein	12	34	428	IPR000770 SAND	6	42
179	IPR001412 Aminoacyl-tRNA synthetase, class I	12	50	429	IPR003072 Orphan nuclear receptor, NOR1 type	6	14
180	IPR002190 MAGE protein	12	26	430	IPR002498 Phosphatidylinositol-4-phosphate 5-kinase	6	12
181	IPR000717 Proteasome component region PCI	12	26	431	IPR000702 Ribosomal protein L6	6	16
182	IPR003309 Transcriptional regulator SCAN	12	294	432	IPR001102 Transglutaminase, N-terminal	6	30
183	IPR000082 SEA	12	137	433	IPR001863 Glypican	6	13
184	IPR001594 Zinc finger, DHHC-type	12	63	434	IPR003406 Glycosyl transferase, family 14	6	6
185	IPR000560 Histidine acid phosphatase	12	99	435	IPR003191 Guanylate-binding protein	6	10
186	IPR001855 Beta defensin	12	17	436	IPR001346 Interferon regulatory factor	5	23
187	IPR005816 Secreted growth factor Wnt protein	11	91	437	IPR002087 Anti-proliferative protein	5	40
188	IPR000467 D111/G-patch	11	55	438	IPR005547 Longevity-assurance protein (LAG1)	5	15
189	IPR000433 Zinc finger, ZZ-type	11	144	439	IPR004839 Aminotransferase, class I and II	5	6
190	IPR001064 Beta and gamma crystallin	11	97	440	IPR002185 Dopamine D4 receptor	5	18
191	IPR004344 Tubulin-tyrosine ligase	11	11	441	IPR000535 Major sperm protein	5	8
192	IPR006670 Cyclin	11	23	442	IPR000329 Uteroglobin subfamily	5	16
193	IPR001124 Lipid-binding serum glycoprotein	11	36	443	IPR000749 ATP:guanido phosphotransferase	5	11
194	IPR002229 Blood group Rhesus C/E and D polypeptide	11	74	444	IPR006187 Claudin tight junction protein	5	13
195	IPR003689 Zinc/iron permease	11	11	445	IPR000602 Glycoside hydrolase, family 38	5	10
196	IPR000425 Major intrinsic protein	11	78	446	IPR000712 Apoptosis regulator Bcl-2, BH	5	34
197	IPR002952 Eggshell protein	11	29	447	IPR008521 Protein of unknown function DUF803	5	5
198	IPR000731 Sterol-sensing 5TM box	11	35	448	IPR006089 Acyl-CoA dehydrogenase	5	24
199	IPR001194 DENN	11	60	449	IPR002867 Zinc finger, C6HC-type	5	16
200	IPR000381 Inhibin, beta B subunit	11	170	450	IPR003397 Mitochondrial import inner membrane translocase, subunit Tim17/22	5	6
201	IPR000795 Protein synthesis factor, GTP-binding	11	100	451	IPR007960 Mammalian taste receptor	5	5
202	IPR005828 General substrate transporter	11	29	452	IPR002554 Protein phosphatase 2A, regulatory B subunit, B56	5	5
203	IPR001699 Transcription factor, T-box	11	94	453	IPR010622 FAST kinase leucine-rich	5	11
204	IPR001159 Double-stranded RNA binding	11	74	454	IPR000641 CbxX/CfqX	5	46
205	IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype	11	44	455	IPR001898 Sodium/sulphate symporter	5	12
206	IPR001487 Bromodomain	11	149	456	IPR000623 Shikimate kinase	5	36
207	IPR001878 Zinc finger, CCHC-type	11	70	457	IPR000557 Calponin repeat	5	70
208	IPR009886 HCaRG	11	11	458	IPR004853 Protein of unknown function DUF250	5	7
209	IPR000500 Connexins	10	87	459	IPR002645 Sulfate transporter/antisigma-factor antagonist STAS	5	18
210	IPR001283 Allergen V5/Tpx-1 related	10	88	460	IPR004686 Tricarboxylate/iron carrier	5	7
211	IPR000648 Oxysterol-binding protein	10	43	461	IPR000582 Acyl-coA-binding protein, ACBP	5	35
212	IPR000591 Pleckstrin/ G-protein, interacting region	10	72	462	IPR001094 Flavodoxin-like	5	63
213	IPR005821 Ion transport	10	29	463	IPR000536 Nuclear hormone receptor, ligand-binding	5	92
214	IPR000337 GPCR, family 3, metabotropic glutamate receptor-like	10	93	464	IPR001925 Porin, eukaryotic type	5	22
215	IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type	10	44	465	IPR002155 Thiolase	5	23
216	IPR000716 Thyroglobulin type-1	10	71	466	IPR002482 Peptidoglycan-binding LysM	5	14
217	IPR000734 Lipase	10	141	467	IPR003511 DNA-binding HORMA	5	9
218	IPR001357 BRCT	10	90	468	IPR001046 Natural resistance-associated macrophage protein	5	57
219	IPR001060 Cdc15/Fes/CIP4	10	50	469	IPR003000 Silent information regulator protein Sir2	5	10
220	IPR011701 Major facilitator superfamily MFS_1	10	11	470	IPR001606 AT-rich interaction region	5	46
221	IPR003347 Transcription factor jumonji/aspartyl beta-hydroxylase	10	18	471	IPR001251 Cellular retinaldehyde-binding/triple function, C-terminal	5	14
222	IPR000644 Cystathionine-beta-synthase	10	71	472	IPR008160 Collagen triple helix repeat	5	9
223	IPR000904 SEC7-like	10	45	473	IPR000853 Nematoda metallothionein, family 6	5	49
224	IPR000164 Histone H3	10	87	474	IPR004877 Cytochrome b561	5	15
225	IPR001173 Glycosyl transferase, family 2	10	12	475	IPR000327 POU-specific	5	68
226	IPR001464 Annexin	10	491	476	IPR001187 Tissue factor	5	17
227	IPR001839 Transforming growth factor beta	10	31	477	IPR000272 FXYD	5	12
228	IPR000566 Lipocalin-related protein and Bos/Can/Equ allergen	10	103	478	IPR002494 Keratin, high sulfur B2 protein	5	5
229	IPR000006 Vertebrate metallothionein	10	90	479	IPR003859 Metazoa galactosyltransferase	5	5
230	IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II	9	213	480	IPR000738 WHEP-TRS	5	55
231	IPR001023 Heat shock protein Hsp70	9	71	481	IPR003438 Glial cell line-derived neurotrophic factor receptor	5	30
232	IPR000286 Histone deacetylase superfamily	9	56	482	IPR001804 Isocitrate/isopropylmalate dehydrogenase, dimeric type	5	14
233	IPR000577 Carbohydrate kinase, FGGY	9	599	483	IPR000239 GPCR kinase	5	65
234	IPR000759 Adrenodoxin reductase	9	158	484	IPR010916 TonB box, N-terminal	5	5
235	IPR001315 Caspase Recruitment	9	62	485	IPR000547 7-Fold repeat in clathrin and VPS proteins	5	50
236	IPR001930 Peptidase M1, membrane alanine aminopeptidase	9	58	486	IPR011021 Arrestin, N-terminal	5	9
237	IPR000237 GRIP	9	32	487	IPR001365 Adenosine/AMP deaminase	5	11
238	IPR007110 Immunoglobulin-like	9	17	488	IPR002589 Appr-1-p processing	5	16
239	IPR000387 Tyrosine specific protein phosphatase and dual specificity protein phosphatase	9	32	489	IPR000402 ATPase, P-type cation exchange, beta subunit	5	14
240	IPR001024 Lipoxygenase, LH2	9	106	490	IPR000725 Olfactory receptor	5	13
241	IPR002999 Tudor	9	60	491	IPR001969 Peptidase aspartic, active site	5	19
242	IPR001876 Zinc finger, RanBP2-type	9	52	492	IPR001881 EGF-like calcium-binding	5	183
243	IPR006052 Tumor Necrosis Factor	9	28	493	IPR002423 Chaperonin Cpn60/TCP-1	5	11
244	IPR001232 SKP1 component	9	15	494	IPR000920 Myelin P0 protein	5	33
245	IPR000217 Tubulin	9	218	495	IPR000620 Protein of unknown function DUF6, transmembrane	5	10
246	IPR005024 Snf7	9	9	496	IPR000375 Dynamin central region	5	44
247	IPR001003 MHC class II, alpha chain, N-terminal	9	34	497	IPR005814 Aminotransferase class-III	5	9
248	IPR002495 Glycosyl transferase, family 8	9	9	498	IPR000174 Interleukin-8 receptor	5	203
249	IPR000001 Kringle	9	251	499	IPR003268 Kir1.1 inward rectifier K+ channel	5	100
250	IPR001373 Cullin	9	33	500	IPR003993 Treacher Collins syndrome protein Treacle	5	23

View top 40 InterPro hits

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