Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000694 Proline-rich region	625	7449	21	IPR007087 Zinc finger, C2H2-type	78	737
2	IPR000719 Protein kinase	508	5086	22	IPR000152 Aspartic acid and asparagine hydroxylation site	76	9602
3	IPR000276 Rhodopsin-like GPCR superfamily	486	18264	23	IPR001092 Basic helix-loop-helix dimerisation region bHLH	74	248
4	IPR000337 GPCR, family 3, metabotropic glutamate receptor-like	239	2824	24	IPR001440 Tetratricopeptide TPR_1	73	1252
5	IPR007086 Zinc finger, C2H2-subtype	178	9720	25	IPR001951 Histone H4	70	505
6	IPR007110 Immunoglobulin-like	172	1111	26	IPR000169 Peptidase, cysteine peptidase active site	66	817
7	IPR000533 Tropomyosin	154	1312	27	IPR000048 IQ calmodulin-binding region	65	1302
8	IPR001680 WD-40 repeat	152	2358	28	IPR002048 Calcium-binding EF-hand	62	617
9	IPR000504 RNA-binding region RNP-1 (RNA recognition motif)	150	1116	29	IPR002198 Short-chain dehydrogenase/reductase SDR	61	914
10	IPR000047 Helix-turn-helix motif, lambda-like repressor	132	1533	30	IPR000108 Neutrophil cytosol factor 2	61	2291
11	IPR000068 Extracellular calcium-sensing receptor	124	12960	31	IPR001064 Beta and gamma crystallin	59	618
12	IPR001611 Leucine-rich repeat	120	1312	32	IPR000051 SAM (and some other nucleotide) binding motif	56	349
13	IPR000315 Zinc finger, B-box	119	3869	33	IPR000379 Esterase/lipase/thioesterase	56	579
14	IPR000008 C2	117	2633	34	IPR005135 Endonuclease/exonuclease/phosphatase	53	80
15	IPR001841 Zinc finger, RING-type	109	360	35	IPR001622 K+ channel, pore region	52	1485
16	IPR001806 Ras GTPase	107	966	36	IPR001478 PDZ/DHR/GLGF	52	338
17	IPR000210 BTB	106	1891	37	IPR000357 HEAT	51	364
18	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	89	846	38	IPR000198 RhoGAP	49	586
19	IPR001128 Cytochrome P450	88	2561	39	IPR000558 Histone H2B	48	425
20	IPR002110 Ankyrin	86	2172	40	IPR000164 Histone H3	47	487

View top 500 InterPro hits (large table)

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