Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000694 Proline-rich region	986	12268	21	IPR001092 Basic helix-loop-helix dimerisation region bHLH	70	368
2	IPR000276 Rhodopsin-like GPCR superfamily	976	22363	22	IPR001781 Zinc finger, LIM-type	68	2588
3	IPR000719 Protein kinase, core	317	6690	23	IPR000742 EGF-like, type 3	67	2492
4	IPR000504 RNA recognition motif, RNP-1	281	2662	24	IPR000169 Peptidase, cysteine peptidase active site	62	997
5	IPR003596 Immunoglobulin V-set, subgroup	269	3504	25	IPR000108 Neutrophil cytosol factor 2	62	1906
6	IPR001680 WD40 repeat	178	3776	26	IPR000372 Leucine-rich repeat, cysteine-rich flanking region, N-terminal	62	1819
7	IPR000210 BTB/POZ-like	160	3660	27	IPR003598 Immunoglobulin subtype 2	62	1046
8	IPR000533 Tropomyosin	160	1797	28	IPR000198 RhoGAP	61	790
9	IPR001841 Zinc finger, RING-type	136	1036	29	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	61	1027
10	IPR000047 Helix-turn-helix motif, lambda-like repressor	136	1788	30	IPR000315 Zinc finger, B-box	60	1409
11	IPR000008 C2 calcium-dependent membrane targeting	134	2815	31	IPR001128 Cytochrome P450	56	1793
12	IPR001806 Ras GTPase	126	1787	32	IPR001478 PDZ/DHR/GLGF	56	724
13	IPR001909 KRAB box	119	1391	33	IPR001664 Intermediate filament protein	55	564
14	IPR002110 Ankyrin	102	2482	34	IPR001452 Src homology-3	55	886
15	IPR001611 Leucine-rich repeat	95	1470	35	IPR000225 Armadillo	55	973
16	IPR000048 IQ calmodulin-binding region	92	2012	36	IPR000104 Antifreeze protein, type I	54	612
17	IPR000152 Aspartic acid and asparagine hydroxylation site	90	9340	37	IPR000637 HMG-I and HMG-Y, DNA-binding	53	648
18	IPR002048 Calcium-binding EF-hand	89	959	38	IPR002126 Cadherin	53	2687
19	IPR001440 Tetratricopeptide TPR_1	81	1966	39	IPR000219 DH	52	915
20	IPR000357 HEAT	70	423	40	IPR007087 Zinc finger, C2H2-type	51	657

View top 500 InterPro hits (large table)

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