Top 500 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000694 Proline-rich region	986	12268	251	IPR000591 Pleckstrin/ G-protein, interacting region	11	156
2	IPR000276 Rhodopsin-like GPCR superfamily	976	22363	252	IPR003689 Zinc/iron permease	11	16
3	IPR000719 Protein kinase, core	317	6690	253	IPR001811 Small chemokine, interleukin-8-like	11	44
4	IPR000504 RNA recognition motif, RNP-1	281	2662	254	IPR004087 K Homology	11	149
5	IPR003596 Immunoglobulin V-set, subgroup	269	3504	255	IPR001357 BRCT	11	226
6	IPR001680 WD40 repeat	178	3776	256	IPR001564 Nucleoside diphosphate kinase, core	11	140
7	IPR000210 BTB/POZ-like	160	3660	257	IPR000904 SEC7-like	11	82
8	IPR000533 Tropomyosin	160	1797	258	IPR000560 Histidine acid phosphatase	11	238
9	IPR001841 Zinc finger, RING-type	136	1036	259	IPR001079 Galectin, galactose-binding lectin	11	107
10	IPR000047 Helix-turn-helix motif, lambda-like repressor	136	1788	260	IPR002049 EGF-like, laminin	11	435
11	IPR000008 C2 calcium-dependent membrane targeting	134	2815	261	IPR004031 PMP-22/EMP/MP20 and claudin	11	86
12	IPR001806 Ras GTPase	126	1787	262	IPR000827 Small chemokine, C-C	11	71
13	IPR001909 KRAB box	119	1391	263	IPR001699 Transcription factor, T-box	11	175
14	IPR002110 Ankyrin	102	2482	264	IPR010989 t-snare	11	12
15	IPR001611 Leucine-rich repeat	95	1470	265	IPR001464 Annexin	11	839
16	IPR000048 IQ calmodulin-binding region	92	2012	266	IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site	11	67
17	IPR000152 Aspartic acid and asparagine hydroxylation site	90	9340	267	IPR001239 Proteinase inhibitor I1, Kazal metazoa	11	171
18	IPR002048 Calcium-binding EF-hand	89	959	268	IPR000910 HMG1/2 (high mobility group) box	11	107
19	IPR001440 Tetratricopeptide TPR_1	81	1966	269	IPR003594 ATP-binding region, ATPase-like	11	65
20	IPR000357 HEAT	70	423	270	IPR000998 MAM	11	195
21	IPR001092 Basic helix-loop-helix dimerisation region bHLH	70	368	271	IPR001063 Ribosomal protein L22/L17	11	45
22	IPR001781 Zinc finger, LIM-type	68	2588	272	IPR001236 Lactate/malate dehydrogenase	11	110
23	IPR000742 EGF-like, type 3	67	2492	273	IPR002394 Nicotinic acetylcholine receptor	11	207
24	IPR000169 Peptidase, cysteine peptidase active site	62	997	274	IPR004299 Membrane bound O-acyl transferase, MBOAT	10	11
25	IPR000108 Neutrophil cytosol factor 2	62	1906	275	IPR000005 Helix-turn-helix, AraC type	10	11287
26	IPR000372 Leucine-rich repeat, cysteine-rich flanking region, N-terminal	62	1819	276	IPR000308 14-3-3 protein	10	110
27	IPR003598 Immunoglobulin subtype 2	62	1046	277	IPR001315 Caspase Recruitment	10	119
28	IPR000198 RhoGAP	61	790	278	IPR000712 Apoptosis regulator Bcl-2, BH	10	76
29	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	61	1027	279	IPR006670 Cyclin	10	48
30	IPR000315 Zinc finger, B-box	60	1409	280	IPR006089 Acyl-CoA dehydrogenase	10	82
31	IPR001128 Cytochrome P450	56	1793	281	IPR007960 Mammalian taste receptor	10	12
32	IPR001478 PDZ/DHR/GLGF	56	724	282	IPR012678 Ribosomal L23 and L15e, core	10	20
33	IPR001664 Intermediate filament protein	55	564	283	IPR001024 Lipoxygenase, LH2	10	237
34	IPR001452 Src homology-3	55	886	284	IPR000695 H+ transporting ATPase, proton pump	10	261
35	IPR000225 Armadillo	55	973	285	IPR002999 Tudor	10	104
36	IPR000104 Antifreeze protein, type I	54	612	286	IPR001734 Na+/solute symporter	10	57
37	IPR000637 HMG-I and HMG-Y, DNA-binding	53	648	287	IPR006052 Tumor Necrosis Factor	10	84
38	IPR002126 Cadherin	53	2687	288	IPR001290 Poly(ADP-ribose) polymerase, catalytic region	10	121
39	IPR000219 DH	52	915	289	IPR005024 Snf7	10	16
40	IPR007087 Zinc finger, C2H2-type	51	657	290	IPR000327 POU-specific	10	182
41	IPR001993 Mitochondrial substrate carrier	50	963	291	IPR000601 PKD	10	118
42	IPR002198 Short-chain dehydrogenase/reductase SDR	49	727	292	IPR001873 Na+ channel, amiloride-sensitive	10	143
43	IPR001356 Homeobox	49	546	293	IPR002125 CMP/dCMP deaminase, zinc-binding	10	35
44	IPR000626 Ubiquitin	47	311	294	IPR000264 Serum albumin	10	147
45	IPR000195 RabGAP/TBC	47	413	295	IPR001373 Cullin	10	51
46	IPR000884 Thrombospondin, type I	46	934	296	IPR001293 Zinc finger, TRAF-type	10	155
47	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	46	344	297	IPR002059 Cold-shock protein, DNA-binding	10	56
48	IPR001304 C-type lectin	45	439	298	IPR001958 Tetracycline resistance protein, TetA	10	84
49	IPR001849 Pleckstrin-like	45	326	299	IPR000331 Rap/ran-GAP	10	57
50	IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type	43	1620	300	IPR005135 Endonuclease/exonuclease/phosphatase	10	48
51	IPR000449 Ubiquitin-associated/Translation elongation factor EF1B, N-terminal	43	581	301	IPR005828 General substrate transporter	10	47
52	IPR001005 SANT, DNA-binding	43	477	302	IPR000956 Stathmin	10	81
53	IPR000886 Endoplasmic reticulum targeting sequence	43	507	303	IPR003597 Immunoglobulin C1-set	10	86
54	IPR000159 Ras-association	41	538	304	IPR001012 UBX	10	65
55	IPR000795 Protein synthesis factor, GTP-binding	41	498	305	IPR003091 Voltage-dependent potassium channel	10	136
56	IPR000980 SH2 motif	41	490	306	IPR000804 Clathrin adaptor, sigma subunit/coatomer, zeta subunit	10	32
57	IPR000215 Protease inhibitor I4, serpin	41	488	307	IPR000569 HECT	10	148
58	IPR007086 Zinc finger, C2H2-subtype	40	1017	308	IPR002164 Nucleosome assembly protein (NAP)	10	10
59	IPR009053 Prefoldin	40	73	309	IPR006020 Phosphotyrosine interaction region	10	30
60	IPR000571 Zinc finger, CCCH-type	40	314	310	IPR000911 Ribosomal protein L11	9	46
61	IPR001623 Heat shock protein DnaJ, N-terminal	39	320	311	IPR003100 Argonaute and Dicer protein, PAZ	9	45
62	IPR000767 Disease resistance protein	39	825	312	IPR001427 Pancreatic ribonuclease	9	54
63	IPR001650 DNA/RNA helicase, C-terminal	38	294	313	IPR008979 Galactose-binding like	9	15
64	IPR003006 Immunoglobulin/major histocompatibility complex motif	38	885	314	IPR001147 Ribosomal protein L21e	9	23
65	IPR002035 von Willebrand factor, type A	37	548	315	IPR000072 Platelet-derived growth factor (PDGF)	9	76
66	IPR000306 Zinc finger, FYVE-type	37	491	316	IPR001494 Importin-beta, N-terminal	9	22
67	IPR000299 Band 4.1, N-terminal	36	727	317	IPR004254 Hly-III related proteins	9	16
68	IPR000608 Ubiquitin-conjugating enzyme, E2	36	202	318	IPR000994 Peptidase M24, catalytic core	9	52
69	IPR001810 Cyclin-like F-box	36	216	319	IPR000517 Ribosomal protein L30	9	27
70	IPR000408 Regulator of chromosome condensation, RCC1	35	918	320	IPR000756 Diacylglycerol kinase accessory region	9	184
71	IPR000436 Sushi/SCR/CCP	35	1603	321	IPR003112 Olfactomedin-like	9	40
72	IPR001660 Sterile alpha motif SAM	34	474	322	IPR000387 Protein-tyrosine phosphatase, Tyr-specific/dual-specificity type	9	47
73	IPR000173 Glyceraldehyde 3-phosphate dehydrogenase	34	247	323	IPR000519 P-type trefoil	9	73
74	IPR003593 AAA+ ATPase, core	33	134	324	IPR001107 Band 7 protein	9	62
75	IPR000340 Protein-tyrosine phosphatase, dual specificity	32	307	325	IPR001305 DnaJ central region	9	142
76	IPR002119 Histone H2A	32	326	326	IPR001251 Cellular retinaldehyde-binding/triple function, C-terminal	9	57
77	IPR000873 AMP-dependent synthetase and ligase	31	162	327	IPR000734 Lipase	9	268
78	IPR000595 Cyclic nucleotide-binding	31	646	328	IPR000731 Sterol-sensing 5TM box	9	40
79	IPR003604 Zinc finger, U1-type	30	578	329	IPR008689 ATPase, F0 complex, subunit D, mitochondrial	9	10
80	IPR000301 CD9/CD37/CD63 antigen	30	267	330	IPR000426 Proteasome alpha-subunit	9	21
81	IPR001766 Fork head transcription factor	29	261	331	IPR001211 Phospholipase A2	9	98
82	IPR000014 PAS	29	542	332	IPR011701 Major facilitator superfamily MFS_1	9	13
83	IPR000480 Glutelin	29	346	333	IPR000538 Link	9	323
84	IPR000488 Death	29	1250	334	IPR009057 Homeodomain-like	9	14
85	IPR000135 High mobility group box HMG1 and HMG2	29	354	335	IPR005076 Glycosyl transferase, family 6	9	15
86	IPR000073 Alpha/beta hydrolase fold-1	29	259	336	IPR001619 Sec1-like protein	9	21
87	IPR001632 G-protein, beta subunit	28	908	337	IPR002017 Spectrin repeat	9	88
88	IPR001752 Kinesin, motor region	28	336	338	IPR000836 Phosphoribosyltransferase	9	30
89	IPR001214 SET	28	499	339	IPR000697 EVH1	9	45
90	IPR001125 Recoverin	28	534	340	IPR000174 Interleukin-8 receptor	9	520
91	IPR000342 Regulator of G protein signalling	27	278	341	IPR003409 MORN motif	9	126
92	IPR000248 Angiotensin II receptor	27	1210	342	IPR000975 Interleukin-1	9	156
93	IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding	27	407	343	IPR006612 Zinc finger, C2CH-type	9	24
94	IPR002190 MAGE protein	27	72	344	IPR006055 Exonuclease	9	37
95	IPR003309 Transcriptional regulator SCAN	27	187	345	IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype	9	45
96	IPR001991 Sodium:dicarboxylate symporter	27	270	346	IPR002108 Actin-binding, cofilin/tropomyosin type	9	56
97	IPR000330 SNF2-related	27	330	347	IPR000009 Protein phosphatase 2A, regulatory subunit PR55	9	313
98	IPR000863 Sulphotransferase	26	36	348	IPR003323 Ovarian tumour, otubain	9	19
99	IPR000418 Ets	26	398	349	IPR000020 Anaphylatoxin/fibulin	9	176
100	IPR000834 Peptidase M14, carboxypeptidase A	26	191	350	IPR005324 Ribosomal protein S5, C-terminal	9	36
101	IPR001757 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter	26	263	351	IPR002091 Aromatic amino acid permease	9	46
102	IPR000175 Sodium:neurotransmitter symporter	26	470	352	IPR002129 Pyridoxal phosphate-dependent decarboxylase	9	66
103	IPR001496 SOCS protein, C-terminal	26	619	353	IPR001863 Glypican	9	23
104	IPR000558 Histone H2B	25	361	354	IPR000562 Type II fibronectin, collagen-binding	9	432
105	IPR001202 WW/Rsp5/WWP	25	358	355	IPR001346 Interferon regulatory factor	8	65
106	IPR000203 GPS	25	862	356	IPR007237 CD20/IgE Fc receptor beta subunit	8	10
107	IPR000483 Cysteine-rich flanking region, C-terminal	25	813	357	IPR002917 GTP-binding protein, HSR1-related	8	38
108	IPR000157 Toll-Interleukin receptor	24	497	358	IPR006594 LisH dimerisation motif	8	32
109	IPR000772 Ricin B lectin	24	311	359	IPR001778 Pollen allergen Poa pIX/Phl pVI, C-terminal	8	53
110	IPR000585 Hemopexin	24	447	360	IPR001902 Sulphate anion transporter	8	83
111	IPR002086 Aldehyde dehydrogenase	24	144	361	IPR006187 Claudin tight junction protein	8	27
112	IPR004000 Actin/actin-like	23	177	362	IPR000054 Ribosomal protein L31e	8	21
113	IPR000629 RNA helicase, ATP-dependent, DEAD-box type	23	152	363	IPR000867 Insulin-like growth factor-binding protein, IGFBP	8	132
114	IPR000253 Forkhead-associated	23	276	364	IPR002052 N-6 Adenine-specific DNA methylase	8	123
115	IPR003656 Zinc finger, BED-type predicted	23	679	365	IPR000469 G-protein alpha subunit, group 12	8	149
116	IPR000324 Vitamin D receptor	23	953	366	IPR000407 Nucleoside phosphatase GDA1/CD39	8	19
117	IPR001965 Zinc finger, PHD-type	23	144	367	IPR002172 Low density lipoprotein-receptor, class A	8	64
118	IPR001878 Zinc finger, CCHC-type	23	155	368	IPR005821 Ion transport	8	16
119	IPR000727 Target SNARE coiled-coil region	22	172	369	IPR001984 Peptidase S16, Lon protease	8	77
120	IPR003961 Fibronectin, type III	22	231	370	IPR004045 Glutathione S-transferase, N-terminal	8	36
121	IPR000003 Retinoid X receptor	22	942	371	IPR000651 Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal	8	124
122	IPR001683 Phox-like	22	100	372	IPR001569 Ribosomal protein L37e	8	20
123	IPR000158 Cell division protein FtsZ	22	1018	373	IPR000817 Prion protein	8	99
124	IPR001675 Glycosyl transferase, family 29	22	42	374	IPR010625 CHCH	8	14
125	IPR000182 GCN5-related N-acetyltransferase	21	48	375	IPR001606 AT-rich interaction region	8	94
126	IPR004843 Metallophosphoesterase	21	152	376	IPR002495 Glycosyl transferase, family 8	8	13
127	IPR001190 Speract/scavenger receptor	21	618	377	IPR001060 Cdc15/Fes/CIP4	8	89
128	IPR000086 NUDIX hydrolase	21	144	378	IPR001791 Laminin G	8	117
129	IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit	21	657	379	IPR003859 Metazoa galactosyltransferase	8	9
130	IPR001526 CD59 antigen	20	54	380	IPR001753 Crotonase, core	8	24
131	IPR001509 NAD-dependent epimerase/dehydratase	20	171	381	IPR000079 High mobility group protein HMG14 and HMG17	8	72
132	IPR000024 Frizzled CRD region	20	306	382	IPR003533 Doublecortin	8	48
133	IPR000421 Coagulation factor 5/8 type, C-terminal	20	795	383	IPR003137 Protease-associated PA	8	18
134	IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit	20	404	384	IPR000322 Glycoside hydrolase, family 31	8	46
135	IPR000233 Cadherin cytoplasmic region	20	986	385	IPR001039 MHC class I, alpha chain, alpha1 and alpha2	8	135
136	IPR000413 Integrins alpha chain	20	482	386	IPR002893 Zinc finger, MYND-type	8	38
137	IPR013026 Tetratricopeptide region	20	83	387	IPR001881 EGF-like calcium-binding	8	279
138	IPR000471 Interferon alpha, beta and delta	20	152	388	IPR000192 Aminotransferase, class V	8	45
139	IPR000500 Connexins	19	235	389	IPR008973 C2 calcium/lipid-binding region, CaLB	8	11
140	IPR000759 Adrenodoxin reductase	19	552	390	IPR000620 Protein of unknown function DUF6, transmembrane	8	18
141	IPR001320 Ionotropic glutamate receptor	19	170	391	IPR007632 Protein of unknown function DUF590	8	11
142	IPR001627 Semaphorin/CD100 antigen	19	234	392	IPR008197 Whey acidic protein, 4-disulphide core	8	63
143	IPR008253 Marvel	19	26	393	IPR003092 Potassium channel TASK	8	118
144	IPR000313 PWWP	19	275	394	IPR000058 Zinc finger, AN1-type	8	76
145	IPR001715 Calponin-like actin-binding	19	127	395	IPR002946 Intracellular chloride channel	8	87
146	IPR001594 Zinc finger, DHHC-type	19	118	396	IPR003080 Glutathione S-transferase, alpha class	8	67
147	IPR003439 ABC transporter related	19	218	397	IPR001173 Glycosyl transferase, family 2	8	12
148	IPR000566 Lipocalin-related protein and Bos/Can/Equ allergen	19	570	398	IPR001375 Peptidase S9, prolyl oligopeptidase active site region	8	91
149	IPR000209 Peptidase S8 and S53, subtilisin, kexin, sedolisin	19	405	399	IPR001932 Protein phosphatase 2C-related	8	27
150	IPR005816 Secreted growth factor Wnt protein	18	226	400	IPR000850 Adenylate kinase	8	80
151	IPR007114 Major facilitator superfamily	18	54	401	IPR001436 Alpha crystallin/Heat shock protein	8	81
152	IPR000326 Phosphoesterase, PA-phosphatase related	18	58	402	IPR002498 Phosphatidylinositol-4-phosphate 5-kinase	8	24
153	IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular	18	80	403	IPR009886 HCaRG	8	12
154	IPR000164 Histone H3	18	175	404	IPR000300 Inositol polyphosphate related phosphatase	8	59
155	IPR000463 Cytosolic fatty-acid binding	18	106	405	IPR004301 Nucleoplasmin	7	14
156	IPR000859 CUB	18	535	406	IPR006651 Kelch	7	113
157	IPR006025 Peptidase M, neutral zinc metallopeptidases, zinc-binding site	18	84	407	IPR000494 EGF receptor, L domain	7	187
158	IPR001751 S100/CaBP-9k-type, calcium binding	17	129	408	IPR001507 Endoglin/CD105 antigen	7	63
159	IPR000467 D111/G-patch	17	148	409	IPR003316 Transcription factor E2F/dimerisation partner (TDP)	7	11
160	IPR000953 Chromo	17	185	410	IPR006662 Thioredoxin-related	7	41
161	IPR002130 Peptidyl-prolyl cis-trans isomerase, cyclophilin-type	17	148	411	IPR002524 Cation efflux protein	7	22
162	IPR002073 3'5'-cyclic nucleotide phosphodiesterase	17	289	412	IPR001382 Glycoside hydrolase, family 47	7	81
163	IPR001007 von Willebrand factor, type C	17	374	413	IPR005834 Haloacid dehalogenase-like hydrolase	7	18
164	IPR002209 Heparin-binding growth factor/Fibroblast growth factor	17	201	414	IPR000190 AT1 angiotensin II receptor	7	424
165	IPR003034 DNA-binding SAP	17	65	415	IPR010370 Transcription elongation factor A, SII-related	7	8
166	IPR001222 Zinc finger, TFIIS-type	17	830	416	IPR002076 GNS1/SUR4 membrane protein	7	16
167	IPR001073 Complement C1q protein	17	186	417	IPR000764 Uridine kinase	7	51
168	IPR000717 Proteasome component region PCI	17	48	418	IPR002909 Cell surface receptor IPT/TIG	7	103
169	IPR001140 ABC transporter, transmembrane region	17	188	419	IPR001876 Zinc finger, RanBP2-type	7	73
170	IPR000033 Low-density lipoprotein receptor, YWTD repeat	17	1788	420	IPR001813 Ribosomal protein 60S	7	23
171	IPR000082 SEA	17	540	421	IPR001925 Porin, eukaryotic type	7	50
172	IPR004827 Basic-leucine zipper (bZIP) transcription factor	17	58	422	IPR000409 Beige/BEACH	7	151
173	IPR001199 Cytochrome b5	17	164	423	IPR003511 DNA-binding HORMA	7	24
174	IPR000095 PAK-box/P21-Rho-binding	17	269	424	IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase	7	11
175	IPR001368 TNFR/CD27/30/40/95 cysteine-rich region	17	277	425	IPR002016 Haem peroxidase, plant/fungal/bacterial	7	28
176	IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II	16	424	426	IPR001950 Translation initiation factor SUI1	7	33
177	IPR001023 Heat shock protein Hsp70	16	201	427	IPR005301 Mob1/phocein	7	17
178	IPR001164 Arf GTPase activating protein	16	267	428	IPR006977 Yip1 domain	7	10
179	IPR001412 Aminoacyl-tRNA synthetase, class I	16	251	429	IPR000089 Biotin/lipoyl attachment	7	75
180	IPR003347 Transcription factor jumonji/aspartyl beta-hydroxylase	16	46	430	IPR001804 Isocitrate/isopropylmalate dehydrogenase	7	31
181	IPR001163 Like-Sm ribonucleoprotein, core	16	51	431	IPR002109 Glutaredoxin	7	47
182	IPR000832 GPCR, family 2, secretin-like	16	724	432	IPR000239 GPCR kinase	7	182
183	IPR000261 EPS15 homology (EH)	16	346	433	IPR001515 Ribosomal protein L32e	7	8
184	IPR000917 Sulphatase	16	52	434	IPR000889 Glutathione peroxidase	7	41
185	IPR000679 Zinc finger, GATA-type	16	212	435	IPR000232 Heat shock factor (HSF)-type, DNA-binding	7	56
186	IPR001844 Chaperonin Cpn60	16	237	436	IPR001969 Peptidase aspartic, active site	7	24
187	IPR001124 Lipid-binding serum glycoprotein	15	53	437	IPR004182 GRAM	7	15
188	IPR002229 Blood group Rhesus C/E and D polypeptide	15	245	438	IPR001089 Small chemokine, C-X-C	7	75
189	IPR008331 Ferritin and Dps	15	66	439	IPR000034 Laminin B	7	972
190	IPR000425 Major intrinsic protein	15	317	440	IPR003663 Sugar transporter	7	80
191	IPR001870 B302, (SPRY)-like	15	277	441	IPR001392 Clathrin adaptor, mu subunit	7	70
192	IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type	15	88	442	IPR000101 Gamma-glutamyltranspeptidase	7	60
193	IPR000001 Kringle	15	624	443	IPR001759 Pentaxin	7	65
194	IPR001111 Transforming growth factor beta (TGFb), N-terminal	15	180	444	IPR003268 Kir1.1 inward rectifier K+ channel	7	175
195	IPR001388 Synaptobrevin	15	111	445	IPR000183 Orn/DAP/Arg decarboxylase 2	7	158
196	IPR001589 Actin-binding, actinin-type	15	577	446	IPR000542 Acyltransferase ChoActase/COT/CPT	7	20
197	IPR001148 Carbonic anhydrase, eukaryotic	15	66	447	IPR001678 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p	7	15
198	IPR001159 Double-stranded RNA binding	15	126	448	IPR000162 Metabotropic glutamate receptor	7	359
199	IPR001487 Bromodomain	15	264	449	IPR001401 Dynamin, GTPase region	7	80
200	IPR000010 Proteinase inhibitor I25, cystatin	15	101	450	IPR001247 Exoribonuclease, phosphorolytic domain 1	7	34
201	IPR000348 emp24/gp25L/p24	14	85	451	IPR000690 Zinc finger, C2H2-type matrin	7	55
202	IPR003599 Immunoglobulin subtype	14	48	452	IPR001590 Peptidase M12B, ADAM/reprolysin	7	106
203	IPR000623 Shikimate kinase	14	137	453	IPR000687 RIO kinase	7	57
204	IPR000716 Thyroglobulin type-1	14	130	454	IPR007052 CS	7	19
205	IPR000837 Fos transforming protein	14	240	455	IPR001630 cAMP response element binding (CREB) protein	7	86
206	IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase	14	48	456	IPR001071 Cellular retinaldehyde binding/alpha-tocopherol transport	7	83
207	IPR001309 Caspase, p20 subunit	14	312	457	IPR001102 Transglutaminase, N-terminal	7	87
208	IPR000644 Cystathionine beta-synthase, core	14	269	458	IPR003406 Glycosyl transferase, family 14	7	10
209	IPR001976 Ribosomal protein S24e	14	27	459	IPR011072 HR1 rho-binding repeat	6	7
210	IPR000223 Peptidase S26A, signal peptidase I	14	197	460	IPR000583 Glutamine amidotransferase, class-II	6	44
211	IPR000577 Carbohydrate kinase, FGGY	13	1586	461	IPR000971 Globin, subset	6	116
212	IPR000333 Activin type II receptor	13	260	462	IPR001221 Phenol hydroxylase reductase	6	94
213	IPR000433 Zinc finger, ZZ-type	13	265	463	IPR001859 Ribosomal protein P2	6	33
214	IPR004344 Tubulin-tyrosine ligase	13	21	464	IPR000799 Steroidogenic acute regulatory protein	6	54
215	IPR000337 GPCR, family 3, metabotropic glutamate receptor-like	13	204	465	IPR000445 Helix-hairpin-helix motif	6	69
216	IPR001770 G-protein, gamma subunit	13	78	466	IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region	6	35
217	IPR000217 Tubulin	13	296	467	IPR003890 MIF4G-like, type 3	6	23
218	IPR000038 Cell division/GTP binding protein	13	66	468	IPR000098 Interleukin-10	6	30
219	IPR001461 Peptidase A1	13	199	469	IPR000602 Glycoside hydrolase, family 38, core	6	29
220	IPR000381 Inhibin, beta B subunit	13	182	470	IPR008962 PapD-like	6	28
221	IPR002659 Glycosyl transferase, family 31	13	15	471	IPR000641 CbxX/CfqX	6	50
222	IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase	13	119	472	IPR003110 Phosphorylated immunoreceptor signaling ITAM	6	29
223	IPR000270 Octicosapeptide/Phox/Bem1p	13	199	473	IPR001360 Glycoside hydrolase, family 1	6	59
224	IPR001855 Beta defensin	13	18	474	IPR000023 Phosphofructokinase	6	125
225	IPR008957 Fibronectin, type III-like fold	13	20	475	IPR001134 Netrin, C-terminal	6	133
226	IPR004367 Cyclin, C-terminal	13	108	476	IPR000557 Calponin repeat	6	153
227	IPR001395 Aldo/keto reductase	13	164	477	IPR004853 Protein of unknown function DUF250	6	10
228	IPR001839 Transforming growth factor beta	13	56	478	IPR000582 Acyl-coA-binding protein, ACBP	6	55
229	IPR001270 Chaperonin clpA/B	12	122	479	IPR002933 Peptidase M20	6	19
230	IPR001064 Beta and gamma crystallin	12	206	480	IPR001094 Flavodoxin-like	6	115
231	IPR000648 Oxysterol-binding protein	12	112	481	IPR001862 Membrane attack complex component/perforin/complement C9	6	43
232	IPR000749 ATP:guanido phosphotransferase	12	53	482	IPR000241 Putative RNA methylase	6	53
233	IPR001553 RecA bacterial DNA recombination	12	63	483	IPR001503 Glycosyl transferase, family 10	6	13
234	IPR007110 Immunoglobulin-like	12	23	484	IPR003000 Silent information regulator protein Sir2	6	18
235	IPR001865 Ribosomal protein S2	12	117	485	IPR007130 Diacylglycerol acyltransferase	6	8
236	IPR013216 Methyltransferase type 11	12	25	486	IPR000272 Ion-transport regulator, FXYD region	6	14
237	IPR012336 Thioredoxin-like fold	12	14	487	IPR006680 Amidohydrolase 1	6	39
238	IPR001194 DENN	12	101	488	IPR002860 Glycoside hydrolase, BNR repeat	6	28
239	IPR005123 2OG-Fe(II) oxygenase	12	56	489	IPR001176 1-aminocyclopropane-1-carboxylate synthase	6	39
240	IPR004841 Amino acid permease-associated region	12	19	490	IPR007084 BRICHOS	6	9
241	IPR001279 Beta-lactamase-like	12	19	491	IPR000454 ATPase, F0 complex, subunit C	6	40
242	IPR000920 Myelin P0 protein	12	200	492	IPR000738 WHEP-TRS	6	102
243	IPR000555 Mov34/MPN/PAD-1	12	37	493	IPR003438 Glial cell line-derived neurotrophic factor receptor	6	44
244	IPR001951 Histone H4	12	120	494	IPR003150 DNA-binding RFX	6	13
245	IPR000243 Peptidase T1A, proteasome beta-subunit	12	61	495	IPR003532 Short hematopoietin receptor, family 2	6	50
246	IPR002123 Phospholipid/glycerol acyltransferase	12	34	496	IPR005334 Tctex-1	6	7
247	IPR000116 High mobility group proteins HMG-I and HMG-Y	12	176	497	IPR002223 Proteinase inhibitor I2, Kunitz metazoa	6	135
248	IPR000286 Histone deacetylase superfamily	11	100	498	IPR006162 Phosphopantetheine attachment site	6	19
249	IPR001283 Allergen V5/Tpx-1 related	11	171	499	IPR001129 Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG)	6	24
250	IPR000434 Polycystic kidney disease type 1 protein	11	168	500	IPR004820 Cytidylyltransferase	6	23

View top 40 InterPro hits

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