Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000276 Rhodopsin-like GPCR superfamily	1156	17742	21	IPR000152 Aspartic acid and asparagine hydroxylation site	89	11649
2	IPR004244 Transposase, L1	929	1186	22	IPR000048 IQ calmodulin-binding region	86	2920
3	IPR000694 Proline-rich region	797	10794	23	IPR001128 Cytochrome P450	82	2142
4	IPR000719 Protein kinase, core	337	5793	24	IPR001440 Tetratricopeptide TPR-1	79	1880
5	IPR003596 Immunoglobulin V-set, subgroup	302	3949	25	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	74	700
6	IPR000477 RNA-directed DNA polymerase (reverse transcriptase)	209	715	26	IPR000104 Antifreeze protein, type I	73	1047
7	IPR000504 RNA recognition motif, RNP-1	181	1485	27	IPR003598 Immunoglobulin subtype 2	67	907
8	IPR000533 Tropomyosin	179	1518	28	IPR000108 Neutrophil cytosol factor 2	65	2152
9	IPR001680 WD40 repeat	177	3814	29	IPR007086 Zinc finger, C2H2-subtype	62	1759
10	IPR000210 BTB/POZ-like	151	3081	30	IPR000372 Leucine-rich repeat, cysteine-rich flanking region, N-terminal	62	1449
11	IPR001909 KRAB box	142	9100	31	IPR000315 Zinc finger, B-box	61	1025
12	IPR001841 Zinc finger, RING-type	136	894	32	IPR001304 C-type lectin	59	434
13	IPR001781 Zinc finger, LIM-type	134	7983	33	IPR000742 EGF-like, type 3	58	1887
14	IPR000008 C2 calcium-dependent membrane targeting	128	2684	34	IPR000357 HEAT	58	416
15	IPR001806 Ras GTPase	127	1544	35	IPR001092 Basic helix-loop-helix dimerisation region bHLH	57	300
16	IPR000047 Helix-turn-helix motif, lambda-like repressor	117	1494	36	IPR001478 PDZ/DHR/GLGF	56	749
17	IPR005135 Endonuclease/exonuclease/phosphatase	95	136	37	IPR000219 DH	55	1103
18	IPR001611 Leucine-rich repeat	95	1353	38	IPR000198 RhoGAP	53	621
19	IPR002048 Calcium-binding EF-hand	92	892	39	IPR001356 Homeobox	52	511
20	IPR002110 Ankyrin	91	2153	40	IPR002198 Short-chain dehydrogenase/reductase SDR	51	652

View top 500 InterPro hits (large table)

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