Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000694 Proline-rich region	562	5751	21	IPR002048 Calcium-binding EF-hand	83	647
2	IPR000719 Protein kinase	429	5256	22	IPR001478 PDZ/DHR/GLGF	75	464
3	IPR000276 Rhodopsin-like GPCR superfamily	377	8019	23	IPR001440 Tetratricopeptide TPR_1	74	1335
4	IPR000504 RNA-binding region RNP-1 (RNA recognition motif)	196	1516	24	IPR001304 C-type lectin	69	584
5	IPR000533 Tropomyosin	187	1425	25	IPR000108 Neutrophil cytosol factor 2	67	1556
6	IPR007110 Immunoglobulin-like	183	1046	26	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	67	630
7	IPR001680 WD-40 repeat	169	2243	27	IPR000198 RhoGAP	65	496
8	IPR007086 Zinc finger, C2H2-subtype	166	5806	28	IPR001356 Homeobox	64	408
9	IPR001611 Leucine-rich repeat	162	1358	29	IPR003961 Fibronectin, type III	63	1282
10	IPR000008 C2 calcium-dependent membrane targeting	156	2091	30	IPR000742 EGF-like, type 3	63	1850
11	IPR001806 Ras GTPase	148	1494	31	IPR001452 Src homology-3	62	758
12	IPR000047 Helix-turn-helix motif, lambda-like repressor	145	1808	32	IPR001128 Cytochrome P450	61	1696
13	IPR001841 Zinc finger, RING-type	143	517	33	IPR002198 Short-chain dehydrogenase/reductase SDR	59	994
14	IPR000210 BTB	132	2045	34	IPR000357 HEAT	59	393
15	IPR007087 Zinc finger, C2H2-type	108	802	35	IPR000219 DH	58	599
16	IPR000152 Aspartic acid and asparagine hydroxylation site	98	6588	36	IPR000242 Tyrosine specific protein phosphatase	55	1088
17	IPR000048 IQ calmodulin-binding region	98	1686	37	IPR000169 Peptidase, cysteine peptidase active site	55	719
18	IPR000315 Zinc finger, B-box	93	1263	38	IPR002492 Transposase, Tc1/Tc3	55	55
19	IPR001092 Basic helix-loop-helix dimerisation region bHLH	93	286	39	IPR001993 Mitochondrial substrate carrier	55	1247
20	IPR002110 Ankyrin	89	1505	40	IPR001849 Pleckstrin-like	54	225

View top 500 InterPro hits (large table)

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